N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfinyl)phenyl)carbamoyl)-2,6-difluorobenzamide CAS 100341-45-5
| CAS No. | 100341-45-5 |
| Molecular Formula | C16H8Cl2F6N2O3S |
| Molecular Weight | 493.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfinyl)phenyl)carbamoyl)-2,6-difluorobenzamide (C16H8Cl2F6N2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfinyl)phenyl)carbamoyl)-2,6-difluorobenzamide (CAS 100341-45-5) is a high-purity analytical reference standard with the molecular formula C16H8Cl2F6N2O3S and a molecular weight of 493.21 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfinyl)phenyl)carbamoyl)-2,6-difluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl2F6N2O3S |
| Molecular Weight | 493.21 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
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- (Z)-3-(2,4-Dichloro-3-methoxy-5-((Z)-4-((4-methoxybenzyl)amino)-4-oxobut-2-en-2-yl)phenyl)-N-ethylbut-2-enamide (CAS 1956426-45-1)
- 2-((N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)-4-methoxyphenyl)sulfonamido)-N,N-dimethylacetamide (CAS 400085-62-3)
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Recommended Standards
- (Z)-[(4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methylidene][(2-chloro-6-fluorophenyl)methoxy]amine (CAS 338416-02-7)
- 4-Chloro-N-((4-((5-chloropyrimidin-2-yl)oxy)-3-nitrophenyl)carbamoyl)-2-nitrobenzamide (CAS 103829-04-5)
- Penciclovir triphosphate (CAS 120082-86-2)
- 1’-Boc-2,7-dibromospiro[fluorene-9,4’-piperidine] (CAS 1616113-98-4)
- 1-(6-Methoxybenzo[d]oxazol-2-yl)ethanamine (CAS 1600439-36-8)
- 4-amino-6-chloropyridine-3-carboxylic acid (CAS 1060811-65-5)
- Ethyl 5-(4-chlorophenyl)-2H-pyrazole-3-carboxylate (CAS 595610-40-5)
- (5R,6R)-decane-5,6-diamine (CAS 872595-15-8)
- Ethyl 2-(2-(4-(trifluoromethoxy)phenyl)hydrazono)propanoate (CAS 883006-93-7)
- 1-((5-Chloro-1,2,3-thiadiazol-4-yl)methyl)piperidin-4-ol (CAS 1154013-26-9)
- 1-(4-Chloro-3-fluorophenyl)cyclopentanamine (CAS 1704112-83-3)
- 1-(4-methylbenzenesulfonyl)azetidin-3-ol (CAS 154010-96-5)
- 1-(Prop-2-yn-1-yl)-1H-benzo[d][1,2,3]triazole (CAS 142321-23-1)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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