2-Iodo-6-(trifluoromethyl)pyridine CAS 100366-74-3
| CAS No. | 100366-74-3 |
| Molecular Formula | C6H3F3IN |
| Molecular Weight | 272.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 272.99 g/mol gives 2-Iodo-6-(trifluoromethyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Iodo-6-(trifluoromethyl)pyridine (CAS 100366-74-3), a certified reference material (molecular formula C6H3F3IN, MW 272.99 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H3F3IN, 2-Iodo-6-(trifluoromethyl)pyridine contains a nitrile group, fluorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3F3IN |
| Molecular Weight | 272.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-Iodo-5-(trifluoromethyl)pyridine (CAS 1214333-22-8)
- 4-Iodo-3-(trifluoromethyl)pyridine (CAS 1412904-86-9)
- 2-Iodo-3-(trifluoromethyl)pyridine (CAS 927434-20-6)
- 2-Iodo-4-(trifluoromethyl)pyridine (CAS 326894-74-0)
- 3-Iodo-2-(trifluoromethyl)pyridine (CAS 590371-71-4)
- 3-Iodo-4-(trifluoromethyl)pyridine (CAS 625115-02-8)
- 4-Iodo-2-(trifluoromethyl)pyridine (CAS 590371-73-6)
- 5-Iodo-2-(trifluoromethyl)pyridine, 97% (CAS 873107-98-3)
Recommended Standards
- 4-Bromo-2,3,5,6-tetrafluorobenzoic acid (CAS 4707-24-8)
- 3,4,6-Trifluoro-2-iodoaniline (CAS 1065101-52-1)
- 3-Bromo-2,4,5,6-tetrafluorobenzoic acid (CAS 33564-64-6)
- 2-Bromo-3,4,5,6-tetrafluorobenzoic acid (CAS 16583-04-3)
- 5-Fluoro-2-nitrobenzoyl chloride, 98% (CAS 394-02-5)
- (4aR,7aR)-Hexahydro-5H-[1,4]dioxino[2,3-c]pyrrole (CAS 1438085-52-9)
- (E)-Dichloro(methyl)(prop-1-en-1-yl)silane (CAS 18142-37-5)
- Methyl (4-bromo-2-cyanophenyl)carbamate (CAS 1217304-77-2)
- 4-((5-Bromo-2-fluorobenzylidene)amino)-3-(2-fluorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 676160-56-8)
- trans-3-Aminocyclopentanol (CAS 167298-58-0)
- Methyl 4,5-dibromo-1H-imidazole-2-carboxylate (CAS 79711-33-4)
- (2S,3S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-methylpentanoic acid (CAS 64339-42-0)
- Ethyl 3-methyl-4-oxocyclohexane-1-carboxylate (CAS 1207529-72-3)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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