2-Iodo-5-trifluoromethyl-pyridine CAS 100366-75-4
| CAS No. | 100366-75-4 |
| Molecular Formula | C6H9F3IN |
| Molecular Weight | 279.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Iodo-5-trifluoromethyl-pyridine is closely related to fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Iodo-5-trifluoromethyl-pyridine (CAS 100366-75-4), a certified reference material (molecular formula C6H9F3IN, MW 279.04 g/mol) for analytical method development and quality control.
The molecular framework of 2-Iodo-5-trifluoromethyl-pyridine (C6H9F3IN) is characterized by fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Iodo-5-trifluoromethyl-pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9F3IN |
| Molecular Weight | 279.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 3-iodo-6-methyl-5-nitropyridin-2-amine (CAS 1000343-76-9)
- 3-Iodo-4-methyl-5-nitropyridin-2-amine (CAS 1935502-16-1)
- (4-Iodo-2-nitrophenyl)hydrazine (CAS 89640-59-5)
- N-(5-Iodo-6-oxo-1,6-dihydropyrimidin-2-yl)acetamide (CAS 2098814-76-5)
- Methyl 5-Iodo-2-oxo-1,2-dihydro-3-pyridinecarboxylate (CAS 116387-40-7)
- (2-Iodo-6-nitrophenyl)methanol (CAS 117847-40-2)
- (2-Iodo-5-nitrophenyl)methanol (CAS 1261611-57-7)
- (3-Iodo-4-nitrophenyl)methanol (CAS 1261794-62-0)
Recommended Standards
- Methyl 5-amino-6-iodopyrazine-2-carboxylate (CAS 1363383-24-7)
- Methyl 6-hydroxy-5-iodonicotinate (CAS 885950-46-9)
- Methyl 3-amino-6-iodopyrazine-2-carboxylate (CAS 1458-16-8)
- 6,8-Dichloro-2,2-difluoro-[1,3]dioxolo[4,5-g]quinazoline (CAS 2306276-15-1)
- 3-(4-Chlorophenyl)propanoic acid (CAS 2019-34-3)
- (S)-N-((1R,2R)-2-(4-Methylbenzamido)cyclohexyl)pyrrolidine-2-carboxamide (CAS 868694-81-9)
- 6-Methyl-5-(2-methylpropyl)pyridine-3-carboxylic acid (CAS 1011558-12-5)
- (R)-2-(Fmoc-amino)-3-[[(allyloxy)carbonyl]amino]propanoic Acid (CAS 178924-05-5)
- (9H-Fluoren-9-yl)methyl (7-hydroxyheptyl)carbamate (CAS 1396968-44-7)
- (S)-2-Amino-2-(3-methoxyphenyl)ethan-1-ol (CAS 1213016-49-9)
- 8-Oxo-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-13-carboxylic acid (CAS 1119452-84-4)
- 2-Carbamoyl-5-cyano-7-nitrobenzo[d]thiazole 3-oxide (CAS 40647-02-7)
- Saxagliptin Impurity 27 (CAS CATO-C4X-104927)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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