4-(Cyclohexyloxy)benzenesulfonyl chloride CAS 100388-99-6
| CAS No. | 100388-99-6 |
| Molecular Formula | C12H15ClO3S |
| Molecular Weight | 274.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Cyclohexyloxy)benzenesulfonyl chloride (CAS 100388-99-6), a certified reference material (molecular formula C12H15ClO3S, MW 274.76 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-(Cyclohexyloxy)benzenesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15ClO3S |
| Molecular Weight | 274.76 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Cyclohexyloxy Standards
- 3-(Cyclohexyloxy)benzenesulfonyl chloride (CAS 1343502-00-0)
- (3-(Cyclohexyloxy)-4-(methoxycarbonyl)phenyl)boronic acid (CAS 855482-72-3)
- 3-(Cyclohexyloxy)-5-hydroxybenzenesulfonamide (CAS 1243367-44-3)
- 3-(Cyclohexyloxy)-2-hydroxybenzenesulfonamide (CAS 1243395-48-3)
- 3-(Cyclohexyloxy)-4-hydroxybenzenesulfonamide (CAS 1243461-40-6)
- 2-(Cyclohexyloxy)-5-hydroxybenzenesulfonamide (CAS 1243479-27-7)
- 2-(Cyclohexyloxy)quinoline-3-carboxylic acid (CAS 88284-21-3)
- 2-(2-(Cyclohexyloxy)ethoxy)ethane-1-sulfonyl chloride (CAS 1343251-89-7)
Recommended Standards
- 4-Decylphenol (CAS 2985-57-1)
- 4-(Cyclopentyloxy)-3-methylbenzenesulfonyl chloride (CAS 1016523-64-0)
- Ruxolitinib Impurity 36 (CAS CATO-C4X-205836)
- 4-(Cyclopentyloxy)-2-methylbenzenesulfonyl chloride (CAS 1016730-44-1)
- TERT-BUTYL 3-((4-AMINO-6-CHLOROPYRIMIDIN-5-YL)OXY)AZETIDINE-1-CARBOXYLATE (CAS 1787294-46-5)
- 2-Isoproxy-3-methylpyridine-5-boronic acid pinacol ester (CAS 1375303-04-0)
- 2-Amino-3-(trifluoromethyl)-3H-imidazo[4,5-f]quinoline (CAS 887267-29-0)
- 8-methoxy-5-methyl-1,2,3,4-tetrahydroquinoline (CAS 953726-89-1)
- 898791-28-1 Cyclobutyl(3,4-difluorophenyl)methanone DTXSID70642552 (CAS 898791-28-1)
- Atrasentan Impurity 94 (CAS 1059043-52-5)
- Methyl 2-(dimethoxymethyl)thiazole-4-carboxylate (CAS 921927-99-3)
- (R)-4-((S)-1-Hydroxypropyl)-1-((R)-1-(4-methoxyphenyl)ethyl)pyrrolidin-2-one (CAS 1650544-76-5)
- tert-Butyl (4-hydroxybicyclo[2.2.2]octan-1-yl)carbamate (CAS 1252672-84-6)
- 30003-72-6 insulin chain b oxidized (CAS 30003-72-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com