Ruxolitinib Impurity 36 CAS CATO-C4X-205836
| CAS No. | CATO-C4X-205836 |
| Molecular Formula | C14H15ClN4 |
| Molecular Weight | 274.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H15ClN4, Ruxolitinib Impurity 36 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ruxolitinib Impurity 36 (CAS CATO-C4X-205836) is a certified pharmaceutical impurity reference standard with the molecular formula C14H15ClN4 and a molecular weight of 274.75 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN4 |
| Molecular Weight | 274.75 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 14 (CAS CATO-C4X-205814)
- Ruxolitinib Impurity 229 (CAS CATO-C4X-2058229)
- Ruxolitinib Impurity 13 (CAS CATO-C4X-2058113)
- Ruxolitinib Impurity 14 (CAS CATO-C4X-2058114)
- Ruxolitinib Impurity 237 (CAS CATO-C4X-2058237)
- Ruxolitinib Impurity 63 (CAS CATO-C4X-205863)
- Ruxolitinib Impurity 118 (CAS CATO-C4X-2058118)
- Ruxolitinib Impurity 107 (CAS CATO-C4X-2058107)
Recommended Standards
- n'-Benzyl-2-chloro-n'-phenylacetohydrazide (CAS 854357-31-6)
- 4-Decylphenol (CAS 2985-57-1)
- N-(3-Amino-4-chlorophenyl)-3-phenylpropanamide (CAS 954583-52-9)
- 4-(Cyclohexyloxy)benzenesulfonyl chloride (CAS 100388-99-6)
- Gatifloxacin Impurity C79 (CAS 182868-72-0)
- Linagliptin Impurity 26 (CAS CATO-C4X-110126)
- Ixazomib Impurity 31 (CAS 50-73-7)
- 231957-54-3 824VSI942Y MIV 150 1-(5-cyanopyridin-2-yl)-3-((1S,2S)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl)urea PC 815 MIV-150 UNII-824VSI942Y (CAS 231957-54-3)
- N-(4-Chlorophenyl)-2-((5-(2-methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 333312-49-5)
- Z-Pro-Hyp-OH (C-2505.0001) (CAS 55878-58-5)
- 2,4-Difluorobenzoyl isothiocyanate (CAS 105534-76-7)
- 6-Methyl-4-(m-tolyl)-5-(3-(p-tolyl)-1,2,4-oxadiazol-5-yl)-3,4-dihydropyrimidine-2(1H)-thione (CAS 892302-22-6)
- Methyl 2,2-difluoro-2-(4-hydroxyphenyl)acetate (CAS 1196147-40-6)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com