Telmisartan Impurity 41 CAS 1004548-55-3
| CAS No. | 1004548-55-3 |
| Molecular Formula | C26H25BrN4 |
| Molecular Weight | 473.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 473.41 g/mol gives Telmisartan Impurity 41 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Telmisartan Impurity 41 (CAS 1004548-55-3) is a certified pharmaceutical impurity reference standard with the molecular formula C26H25BrN4 and a molecular weight of 473.41 g/mol.
Structurally, Telmisartan Impurity 41 (C26H25BrN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 473.41 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25BrN4 |
| Molecular Weight | 473.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Telmisartan Standards
- Telmisartan Impurity 64 (CAS CATO-C4X-135964)
- Telmisartan Impurity 102 (CAS CATO-C4X-1359102)
- Telmisartan Impurity 25 (CAS CATO-C4X-135925)
- Telmisartan Impurity 101 (CAS 1338830-39-9)
- Telmisartan EP Impurity G (CAS 144702-27-2)
- Telmisartan Impurity 83 (CAS CATO-C4X-135983)
- Telmisartan Impurity 24 (CAS 144701-81-5)
- Telmisartan Impurity 26 (CAS CATO-C4X-135926)
Recommended Standards
- S-(2,4-Dinitrophenyl)-Glutathione (CAS 26289-39-4)
- 7-Fluoro-3-oxo-2-(2-(pyridin-2-yl)ethyl)-N-(4-(trifluoromethoxy)benzyl)isoindoline-1-carboxamide (CAS 1198117-23-5)
- 4-Methylsulfonyl-2,2',3',4',5,5',6-heptachlorobiphenyl (CAS 153310-30-6)
- Fmoc-2-F-L-Phe(4-CF3)-OH (CAS 2349352-61-8)
- Daptomycin Impurity 21 (CAS CATO-C4X-137821)
- Nifedipine EP Impurity B (CAS 50428-14-3)
- Milrinone Impurity 32 (CAS CATO-C4X-109132)
- 1a,2,3,7b-Tetrahydronaphtho-[1,2-b]oxirene-1a-carboxylic acid (CAS 864130-77-8)
- ((3S,6S)-1,1-Difluoro-5-methyl-5-azaspiro[2.4]heptan-6-yl)methanol (CAS 2850326-68-8)
- 3-Bromo-6-chloroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 923225-00-7)
- N-(1-(2-Hydroxyethyl)pyrrolidin-3-yl)-N-methylacetamide (CAS 1353945-03-5)
- 2-Bromo-1-(1-methylcyclopropyl)ethan-1-one (CAS 76714-45-9)
- 2-(Pentafluoroethoxy)ethan-1-amine hydrochloride (CAS 1286743-86-9)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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