Nifedipine EP Impurity B CAS 50428-14-3
| CAS No. | 50428-14-3 |
| Molecular Formula | C17H16N2O5 |
| Molecular Weight | 328.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nifedipine EP Impurity B (C17H16N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Nifedipine EP Impurity B (CAS 50428-14-3), a pharmacopoeial impurity reference standard (molecular formula C17H16N2O5, MW 328.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nifedipine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H16N2O5 |
| Molecular Weight | 328.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 2 |
Related Nifedipine Standards
- Nifedipine Impurity 25 (CAS 73372-63-1)
- Nifedipine Impurity 10 (CAS 114709-68-1)
- Nifedipine Impurity 8 (CAS 74936-71-3)
- Nifedipine Impurity 29 (CAS CATO-C4X-141029)
- Nifedipine EP Impurity A (CAS 67035-22-7)
- Nifedipine impurity 38 (CAS CATO-C4X-141038)
- Nifedipine Metabolite (CAS 34783-31-8)
- Nifedipine Impurity 9 (CAS 21829-09-4)
Recommended Standards
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- Semaglutide impurity 88 (CAS CATO-C4X-222688)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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