4-(Difluoromethyl)-6-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-2-hydrazinylpyrimidine CAS 1004644-07-8
| CAS No. | 1004644-07-8 |
| Molecular Formula | C11H14F2N6 |
| Molecular Weight | 268.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Difluoromethyl)-6-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-2-hydrazinylpyrimidine (CAS 1004644-07-8) is a high-purity analytical reference standard with the molecular formula C11H14F2N6 and a molecular weight of 268.27 g/mol.
The molecular framework of 4-(Difluoromethyl)-6-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-2-hydrazinylpyrimidine (C11H14F2N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14F2N6 |
| Molecular Weight | 268.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3,6-dimethoxypyridine-5-sulfonamide (CAS 1803709-61-6)
- 2-(Difluoromethyl)-3,5-dimethoxypyridine-6-sulfonamide (CAS 1805162-30-4)
- 2-(Difluoromethyl)-3,4-dimethoxypyridine-5-sulfonamide (CAS 1805255-29-1)
- 4-(Difluoromethyl)-2,6-dimethoxypyridine-3-sulfonamide (CAS 1805337-09-0)
- 2-(Difluoromethyl)-3,4-dimethoxypyridine-6-sulfonamide (CAS 1806801-23-9)
- 2-(Difluoromethyl)-3-hydroxy-5-(trifluoromethoxy)pyridine-6-acetonitrile (CAS 1803959-84-3)
- 2-(4-(Difluoromethyl)-2-hydroxy-6-(trifluoromethoxy)pyridin-3-yl)acetonitrile (CAS 1804347-30-5)
- 2-(4-(Difluoromethyl)-6-hydroxy-5-(trifluoromethoxy)pyridin-2-yl)acetonitrile (CAS 1804360-63-1)
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