Quinoline-8-carbonyl chloride CAS 100517-41-7
| CAS No. | 100517-41-7 |
| Molecular Formula | C10H6ClNO |
| Molecular Weight | 191.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Quinoline-8-carbonyl chloride (C10H6ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Quinoline-8-carbonyl chloride (CAS 100517-41-7), molecular formula C10H6ClNO and molecular weight 191.61 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Quinoline-8-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO |
| Molecular Weight | 191.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Quinoline Standards
- Quinoline-3-carbonyl chloride (CAS 84741-86-6)
- Quinoline-4-carbonyl chloride (CAS 50821-72-2)
- Quinoline-6-carbonyl chloride (CAS 72369-87-0)
- Quinoline-7-carbonyl chloride (CAS 206257-00-3)
- Quinoline-8-sulfinic acid (CAS 41857-93-6)
- Quinoline-5,8-dithiol (CAS 39103-20-3)
- Quinoline, 1-butyl-1,2,3,4-tetrahydro- (CAS 6613-30-5)
- Methyl quinoline-1(2H)-carboxylate (CAS 17718-14-8)
Recommended Standards
- Raltitrexed Impurity 4 (CAS 39978-57-9)
- Isoquinoline-6-carbonyl chloride (CAS 1105710-41-5)
- 5-Nitrothiophene-3-carbonyl chloride (CAS 91538-55-5)
- 3-Chloroquinoline-2-carbaldehyde (CAS 1169394-26-6)
- 1-(2-(2,5-Dichlorophenyl)cyclopropyl)-N-methylmethanamine (CAS 1315372-50-9)
- (1H-pyrrolo[2,3-c]pyridin-4-yl)methanol (CAS 1352395-31-3)
- 1-Ethyl-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (CAS 875224-04-7)
- tert-Butyl 2-(2-ethoxy-2-oxoethyl)-1H-indole-1-carboxylate (CAS 172226-77-6)
- (4-(Isobutylamino)piperidin-4-yl)methanol (CAS 1250086-33-9)
- 3-(p-Tolyl)pyrimidin-4(3H)-one (CAS 109853-42-1)
- (S)-(-)-1-(4-bromophenyl)ethylisothiocyanate (CAS 745784-02-5)
- 2-(2-Amino-4-phenyl-1,3-thiazol-5-yl)acetic acid (CAS 49779-98-8)
- 3-(Phenylsulfonyl)azetidine hydrochloride (CAS 1820741-25-0)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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