1-(2,2-Difluoroethyl)-3-methoxy-1h-pyrazol-4-amine CAS 1006462-58-3
| CAS No. | 1006462-58-3 |
| Molecular Formula | C6H9F2N3O |
| Molecular Weight | 177.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)-3-methoxy-1h-pyrazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2,2-Difluoroethyl)-3-methoxy-1h-pyrazol-4-amine (CAS 1006462-58-3), molecular formula C6H9F2N3O and molecular weight 177.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,2-Difluoroethyl)-3-methoxy-1h-pyrazol-4-amine (C6H9F2N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H9F2N3O |
| Molecular Weight | 177.15 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoroethyl Standards
- 5-(2,2-Difluoroethyl)piperidine-2,4-dione (CAS 2767411-68-5)
- 1-(2,2-Difluoroethyl)-4-nitro-1h-pyrazole (CAS 1006442-51-8)
- 1-(2,2-Difluoroethyl)-3-nitro-1h-pyrazole (CAS 1171087-45-8)
- 1-(2,2-Difluoroethyl)-5-nitro-1h-pyrazole (CAS 1171325-18-0)
- (2,2-difluoroethyl)(3,4-dihydro-2H-pyran-2-ylmethyl)amine (CAS 1545665-02-8)
- 3-(1,1-Difluoroethyl)isoxazole-4-carboxylic acid (CAS 2452464-87-6)
- 3-(2,2-Difluoroethyl)isoxazole-4-carboxylic acid (CAS 2452464-95-6)
- 2,2-Difluoroethyl 2,2,2-trifluoroacetate (CAS 7556-84-5)
Recommended Standards
- Diethyl Cyanomethylphosphonate (CAS 2537-48-6)
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- 5-(Trifluoromethyl)thiophene-2-carbonitrile (CAS 1260670-70-9)
- 4-(5-(1-Isopropylpyrrolidin-2-yl)-6-methylpyridin-2-yl)morpholine (CAS 1352531-31-7)
- 4-(4-Cyanophenyl)bicyclo[2.2.2]Octane-1-carboxylic acid (CAS 1773510-18-1)
- 2-(2,6-Dimethoxyphenyl)ethan-1-ol (CAS 14534-76-0)
- (3,4-Difluoro-5-methylphenyl)methanol (CAS 1379173-53-1)
- Ethane-1,1,1-d3 (gas) (CAS 2031-95-0)
- N-((1H-Benzo[d]imidazol-1-yl)methyl)formamide (CAS 87022-34-2)
- 2-((4-Chlorophenyl)thio)-5-nitrobenzonitrile (CAS 78940-73-5)
- 3-((2-Fluorobenzyl)oxy)benzoic acid (CAS 938138-15-9)
- 5-Bromo-4-methoxy-1-methyl-1,3-dihydro-indol-2-one (CAS 1255957-66-4)
- Peptide 441 (CAS CATO-CPTD788441)
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