5-(2,2-Difluoroethyl)piperidine-2,4-dione CAS 2767411-68-5
| CAS No. | 2767411-68-5 |
| Molecular Formula | C7H9F2NO2 |
| Molecular Weight | 177.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2,2-Difluoroethyl)piperidine-2,4-dione.
CATO supplies 5-(2,2-Difluoroethyl)piperidine-2,4-dione (CAS 2767411-68-5), a certified reference material (molecular formula C7H9F2NO2, MW 177.15 g/mol) for analytical method development and quality control.
5-(2,2-Difluoroethyl)piperidine-2,4-dione (C7H9F2NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(2,2-Difluoroethyl)piperidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9F2NO2 |
| Molecular Weight | 177.15 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)-3-methoxy-1h-pyrazol-4-amine (CAS 1006462-58-3)
- 1-(2,2-Difluoroethyl)-4-nitro-1h-pyrazole (CAS 1006442-51-8)
- 1-(2,2-Difluoroethyl)-3-nitro-1h-pyrazole (CAS 1171087-45-8)
- 1-(2,2-Difluoroethyl)-5-nitro-1h-pyrazole (CAS 1171325-18-0)
- (2,2-difluoroethyl)(3,4-dihydro-2H-pyran-2-ylmethyl)amine (CAS 1545665-02-8)
- 3-(1,1-Difluoroethyl)isoxazole-4-carboxylic acid (CAS 2452464-87-6)
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Recommended Standards
- 2-(trifluoromethyl)thiophene-3-carbonitrile (CAS 2060062-40-8)
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- 6-Methyl-5-nitro-7H-pyrrolo[2,3-b]pyridine (CAS 1000340-19-1)
- N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-seryl-L-proline (CAS 143038-46-4)
- 1-(1-(tert-Butyl)-1H-pyrrol-2-yl)-2,2,2-trifluoroethanone (CAS 74889-35-3)
- 3-((4-Chlorophenyl)sulfonyl)-1-(3,4-dimethoxyphenyl)propan-1-one (CAS 720667-92-5)
- N-(2-Amino-2-oxoethyl)-2-(pyrazine-2-carboxamido)oxazole-4-carboxamide (CAS 1396882-38-4)
- 1,4,5,8-Tetraamino-2,7-bis(3-ethylphenoxy)anthracene-9,10-dione (CAS 88600-67-3)
- 6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1076197-93-7)
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