5-(1,3-Dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride CAS 1006481-23-7
| CAS No. | 1006481-23-7 |
| Molecular Formula | C13H9ClF3N5O |
| Molecular Weight | 343.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(1,3-Dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(1,3-Dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (CAS 1006481-23-7) is a high-purity analytical reference standard with the molecular formula C13H9ClF3N5O and a molecular weight of 343.69 g/mol.
5-(1,3-Dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride (C13H9ClF3N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(1,3-Dimethyl-1h-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClF3N5O |
| Molecular Weight | 343.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Dimethyl Standards
- 4,6-Dimethyl-2-(((5-(methylthio)-4-phenyl-4H-1,2,4-triazol-3-yl)methyl)thio)pyrimidine (CAS 485327-84-2)
- 2,6-Dimethyl-4-[2-(phenylsulfanyl)acetyl]phenyl N,N-dimethylcarbamate (CAS 339101-02-9)
- N-{5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}methanesulfonamide (CAS 338954-71-5)
- N-{5,6-dimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}methanesulfonamide (CAS 338423-67-9)
- 3-{5,6-dimethyl-1-[(2-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 860787-66-2)
- 3-{5,6-dimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 860787-74-2)
- 3-{5,6-dimethyl-1-[(4-methylphenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one (CAS 860787-64-0)
- Ethyl 1-((6,7-dimethyl-2-oxo-2H-chromen-4-yl)methyl)piperidine-4-carboxylate (CAS 854130-45-3)
Recommended Standards
- Octachlorocyclopentene (CAS 706-78-5)
- (E)-{amino[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}amino benzoate (CAS 338791-59-6)
- Glycidyl palmitate-d31 (palmitate d31) (CAS 1246819-24-8)
- (E)-2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazono)methyl)benzoic acid (CAS 338795-35-0)
- 4-[2-(4-Chloro-3-methylphenoxy)ethyl]piperidinehydrochloride (CAS 1219981-23-3)
- PD 160170 (CAS 181468-88-2)
- 2-(3-Fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1554286-01-9)
- Furosine (CAS 19746-33-9)
- Ammonium hexachloroiridate(III) hydrate (CAS 29796-57-4)
- (4-(Cyclohexylcarbamoyl)-2-fluorophenyl)boronic acid (CAS 874289-27-7)
- 5-[(4,6-Dimethylpyrimidin-2-yl)amino]-2-hydroxybenzoic acid (CAS 876455-22-0)
- (4,6-Dichloro-2-(methylthio)pyrimidin-5-yl)(phenyl)methanol (CAS 1137576-47-6)
- N-(4-Bromo-3-methylphenyl)-5,7-dichlorothiazolo[4,5-d]pyrimidine-2-sulfonamide (CAS 1000573-10-3)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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