Ethyl 8-formyl-1,4-dioxaspiro[4.5]decane-8-carboxylate CAS 1006686-08-3
| CAS No. | 1006686-08-3 |
| Molecular Formula | C12H18O5 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 8-formyl-1,4-dioxaspiro[4.5]decane-8-carboxylate (CAS 1006686-08-3), molecular formula C12H18O5 and molecular weight 242.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 8-formyl-1,4-dioxaspiro[4.5]decane-8-carboxylate (C12H18O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18O5 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
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Recommended Standards
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- 2-Isopropoxy-5-nitropyrimidine (CAS 14998-03-9)
- ((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 143028-99-3)
- Propyl (3-methylbenzofuran-2-yl)carbamate (CAS 61307-28-6)
- (3-Fluoro-2-methoxyphenyl)methanol (CAS 303043-91-6)
- 4-Hydroxybenzenesulfonic Acid Ammonium Salt (CAS 856777-15-6)
- (3-((Phenylamino)methyl)phenyl)boronic acid (CAS 690957-43-8)
- 2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (CAS 1174312-44-7)
- [4-(2-methylpropyl)phenyl](thiophen-2-yl)methanone (CAS 863669-60-7)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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