Paliperidone Impurity 16 CAS 1006685-69-3
| CAS No. | 1006685-69-3 |
| Molecular Formula | C24H27FN4O5 |
| Molecular Weight | 470.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Paliperidone Impurity 16 (CAS 1006685-69-3), a pharmacopoeial impurity reference standard (molecular formula C24H27FN4O5, MW 470.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Paliperidone Impurity 16 (C24H27FN4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Paliperidone Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H27FN4O5 |
| Molecular Weight | 470.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Paliperidone Standards
- Paliperidone Impurity 80 (CAS 130049-87-5)
- Paliperidone Impurity 64 (CAS 1415488-05-9)
- Paliperidone Impurity 71 (CAS CATO-C4X-172471)
- Paliperidone Impurity 147 (CAS CATO-C4X-1724147)
- Paliperidone Impurity 32 (CAS 1141761-80-9)
- Paliperidone Impurity 23 (CAS CATO-C4X-1724123)
- Paliperidone Impurity 34 (CAS CATO-C4X-1724134)
- Paliperidone Impurity 27 (CAS 1388021-46-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com