1-(4-Chloro-2-nitrophenyl)-1h-pyrazole-4-carboxylic acid CAS 1006952-38-0
| CAS No. | 1006952-38-0 |
| Molecular Formula | C10H6ClN3O4 |
| Molecular Weight | 267.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chloro-2-nitrophenyl)-1h-pyrazole-4-carboxylic acid.
1-(4-Chloro-2-nitrophenyl)-1h-pyrazole-4-carboxylic acid (CAS 1006952-38-0), molecular formula C10H6ClN3O4 and molecular weight 267.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Chloro-2-nitrophenyl)-1h-pyrazole-4-carboxylic acid (C10H6ClN3O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Chloro-2-nitrophenyl)-1h-pyrazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClN3O4 |
| Molecular Weight | 267.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetate (CAS 1053656-47-5)
- 2-Chloro-n-{[4-(trifluoromethoxy)phenyl]methyl}acetamide (CAS 1094533-49-9)
- Ethyl 2-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)acetate (CAS 1219950-27-2)
- Ethyl 2-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)acetate (CAS 1373253-50-9)
- Ethyl 2-(2-chloro-5-(trifluoromethyl)pyridin-4-yl)acetate (CAS 1393543-36-6)
- Ethyl 2-(4-chloro-6-(trifluoromethyl)pyridin-3-yl)acetate (CAS 1393544-39-2)
- Ethyl 2-(4-chloro-2-(trifluoromethyl)pyridin-3-yl)acetate (CAS 1393544-47-2)
- Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-4-yl)acetate (CAS 1393560-65-0)
Recommended Standards
- 5-(4-Chloro-2-nitrophenyl)furan-2-carboxylic acid (CAS 95611-88-4)
- 5-(2-Chloro-5-nitrophenyl)-2-furoic acid, 97% (CAS 207399-28-8)
- 2,2,2-trifluoroethyl 5-chloro-2-methylphenylcarbamate (CAS 1087788-56-4)
- 5-(2-Chloro-4-nitrophenyl)furan-2-carboxylic acid (CAS 207399-26-6)
- 1-Chloro-3-methylbut-3-en-2-one (CAS 193958-16-6)
- Nickel(II) Benzenesulfonate Hexahydrate (CAS 39819-65-3)
- 5-Chloro-2-(oxolan-3-yloxy)benzonitrile (CAS 1375471-48-9)
- 2-(4-Benzoylphenyl)-2-(4-fluorophenyl)acetamide (CAS 860609-43-4)
- ((2-(2-Iodophenyl)propan-2-yl)oxy)(trifluoromethyl)sulfane (CAS 1584705-82-7)
- 4,6-Dibromo-2-(3-iodophenyl)-2H-benzo[d][1,2,3]triazol-5-amine (CAS 1706437-39-9)
- 2-Bromo-3-(benzyloxy)-6-fluorobenzoic acid (CAS 2432848-53-6)
- Itraconazole Impurity 48 (CAS CATO-C4X-149748)
- 3-((2-Aminoethyl)thio)-1-(4-fluorophenyl)pyrrolidine-2,5-dione (CAS 400063-27-6)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com