Itraconazole Impurity 48 CAS CATO-C4X-149748
| CAS No. | CATO-C4X-149748 |
| Molecular Formula | C39H36Cl2N8O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Itraconazole Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Itraconazole Impurity 48 (CAS CATO-C4X-149748), a pharmacopoeial impurity reference standard (molecular formula C39H36Cl2N8O6, MW 783.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Itraconazole Impurity 48 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 783.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C39H36Cl2N8O6 |
| Molecular Weight | 783.67 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Diazoxide impurity 4 (CAS 34005-11-3)
- Ketorolac impurity 74 (CAS CATO-C4X-166974)
- Esomeprazole Impurity 144 (CAS CATO-C4X-1112144)
- Strontium bromide hexahydrate (CAS 7789-53-9)
- 2-Chlorothiazolo[4,5-b]pyrazine (CAS 1190927-25-3)
- Dichlorobis[2-(di-t-butylphosphino)ethylamine]ruthenium (II) (CAS 1092372-91-2)
- 5-((4-Chlorophenyl)amino)-3-methylbenzo[c]isoxazole-4,7-dione (CAS 51485-59-7)
- Paricalcitol Impurity 30 (CAS 139356-38-0)
- (4-Methoxy-3-propoxyphenyl)boronic acid (CAS 150145-31-6)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com