Prochlorperazine EP Impurity A CAS 10078-27-0
| CAS No. | 10078-27-0 |
| Molecular Formula | C20H24ClN3OS |
| Molecular Weight | 389.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Prochlorperazine EP Impurity A is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Prochlorperazine EP Impurity A (CAS 10078-27-0, C20H24ClN3OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Prochlorperazine EP Impurity A (C20H24ClN3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Prochlorperazine EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H24ClN3OS |
| Molecular Weight | 389.94 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Prochlorperazine Standards
- Prochlorperazine Maleate (CAS 88021-18-5)
- Prochlorperazine RC 3 (CAS 54241-02-0)
- Prochlorperazine Impurity 6 (CAS CATO-C4X-19666)
- Prochlorperazine Impurity 9 (CAS 109095-35-4)
- Prochlorperazine RC 1 (CAS 67293-64-5)
- Prochlorperazine Sulfoxide-d3 (CAS 1189943-37-0)
- Prochlorperazine Impurity 7 (CAS CATO-C4X-19667)
- Prochlorperazine-d8 Dimaleate (CAS 1215641-01-2)
Recommended Standards
- 1,2-Diiodo-4,5-dimethoxybenzene (CAS 110190-08-4)
- (4,5-Diiodo-1,2-phenylene)dimethanol (CAS 53279-73-5)
- n-[3-(4-tert-Butylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-chloroacetamide (CAS 792954-19-9)
- [4-(hydroxymethyl)-2,5-diiodophenyl]methanol (CAS 915706-87-5)
- Bacitracin Impurity A (CAS CATO-C4X-15531)
- Carbazochrome Impurity 14 (CAS CATO-C4X-229114)
- Cefovecin impurity 9 (CAS CATO-C4X-30359)
- N-((1-Cyclohexyl-1H-tetrazol-5-yl)methyl)-2,4-dimethoxybenzamide (CAS 921144-03-8)
- 3-Amino-3-(4-bromothiophen-2-yl)propan-1-ol (CAS 683220-46-4)
- 3-Amino-4-methoxy-N-methylbenzenesulfonamide (CAS 99969-26-3)
- Amiodarone Impurity 13 (CAS 83790-87-8)
- Fmoc-β-Ala-OPfp (CAS 149303-38-8)
- N-hydroxy-2-methylbenzamide (CAS 17512-73-1)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com