4-((3-(4-Carboxybenzyl)-2,4-dioxothiazolidin-5-yl)amino)benzoic acid CAS 1008710-58-4
| CAS No. | 1008710-58-4 |
| Molecular Formula | C18H14N2O6S |
| Molecular Weight | 386.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-((3-(4-Carboxybenzyl)-2,4-dioxothiazolidin-5-yl)amino)benzoic acid (CAS 1008710-58-4), molecular formula C18H14N2O6S and molecular weight 386.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((3-(4-Carboxybenzyl)-2,4-dioxothiazolidin-5-yl)amino)benzoic acid (C18H14N2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H14N2O6S |
| Molecular Weight | 386.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Carboxybenzyl Standards
- N-Carboxybenzyl Gemcitabine (CAS 138685-83-3)
- 1,4-Bis(4-carboxybenzyl)-1-methylpiperazin-1-ium (Imatinib Impurity) (CAS 1407229-73-5)
- 5-(4-Carboxybenzyl)-4-oxo-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine-2-carboxylic acid (CAS 2007910-07-6)
- 5-(Bis(4-carboxybenzyl)amino)-isophthalic acid (CAS 1492054-35-9)
- 5-((4-Carboxybenzyl)oxy)isophthalic acid (CAS 1050912-62-3)
- 5-((2-Carboxybenzyl)oxy)isophthalic acid (CAS 1365694-39-8)
- 4-((4-Carboxybenzyl)oxy)benzoic acid (CAS 345221-90-1)
- N-Carboxybenzyl-L-allothreonine Methyl Ester (CAS 98777-34-5)
Recommended Standards
- N-Methyl-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338781-63-8)
- ((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl sulfamate (CAS 112921-00-3)
- N-benzyl-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-04-6)
- 5-(2-Hydroxy-6-oxo-cyclohex-1-enecarbonyl)-2-methanesulfonyl-4-oxazol-2-yl-benzonitrile (CAS 1231559-71-9)
- 2-Ethyl-N-(3-methyl-1-(6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-5-yl)butanamide (CAS 1004253-91-1)
- methyl thieno[3,2-c]pyridine-6-carboxylate (CAS 253332-82-0)
- N-{4-[2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl]-1,3-thiazol-2-yl}cyclohexanecarboxamide (CAS 866041-03-4)
- Oseltamivir Impurity 243 (CAS CATO-C4X-1720243)
- Methyl 4-((5-bromo-2-hydroxybenzylidene)amino)-3-fluorobenzoate (CAS 1296225-21-2)
- 3-{1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}-1-[2-(propan-2-yl)phenyl]urea (CAS 1796921-00-0)
- 4-(Furan-2-yl)thiophene-2-carboxylic acid (CAS 893727-89-4)
- Pyridine-3,4-dicarboxylic Anhydride (CAS 4664-08-8)
- (2S,3S)-3-Phenylpyrrolidine-2-carboxylic acid (CAS 118758-49-9)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com