N-Carboxybenzyl Gemcitabine CAS 138685-83-3
| CAS No. | 138685-83-3 |
| Molecular Formula | C17H17F2N3O6 |
| Molecular Weight | 397.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 397.33 g/mol gives N-Carboxybenzyl Gemcitabine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-Carboxybenzyl Gemcitabine (CAS 138685-83-3) is a high-purity analytical reference standard with the molecular formula C17H17F2N3O6 and a molecular weight of 397.33 g/mol.
N-Carboxybenzyl Gemcitabine (C17H17F2N3O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17F2N3O6 |
| Molecular Weight | 397.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- Ferricsalicylate (CAS 30492-15-0)
- 3-Phenylpropiolamide (CAS 7223-30-5)
- 2-(2-Amino-6-(difluoromethyl)-3-methoxypyridin-4-yl)acetic acid (CAS 1806899-08-0)
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