Propofol EP Impurity I CAS 101-84-8

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.101-84-8
Molecular FormulaC12H10O
Molecular Weight170.21 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Propofol EP Impurity I CAS 101-84-8 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Propofol EP Impurity I (CAS 101-84-8), a pharmacopoeial impurity reference standard (molecular formula C12H10O, MW 170.21 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a hydroxyl group, an ether linkage, an aromatic ring system, Propofol EP Impurity I is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 170.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H10O
Molecular Weight170.21 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957

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