2-Chlorothiazole-5-carboxylic acid CAS 101012-12-8
| CAS No. | 101012-12-8 |
| Molecular Formula | C4H2ClNO2S |
| Molecular Weight | 163.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Chlorothiazole-5-carboxylic acid (CAS 101012-12-8), a certified reference material (molecular formula C4H2ClNO2S, MW 163.58 g/mol) for analytical method development and quality control.
Based on its molecular formula C4H2ClNO2S, 2-Chlorothiazole-5-carboxylic acid contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 163.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Chlorothiazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2ClNO2S |
| Molecular Weight | 163.58 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorothiazole Standards
- 5-Chlorothiazole-2-carboxylic Acid (CAS 101012-16-2)
- 4-Chlorothiazole-2-carboxylic acid (CAS 1211521-70-8)
- 5-Chlorothiazole-4-carboxylic acid (CAS 1505987-37-0)
- 2-Chlorothiazole-4-carboxylic Acid (CAS 5198-87-8)
- 2-Chlorothiazole-4-carboxamide (CAS 928256-35-3)
- 2-Chlorothiazole-5-carboxamide (CAS 761454-63-1)
- 5-Chlorothiazole-2-carboxamide (CAS 98027-07-7)
- Methyl 4-chlorothiazole-5-carboxylate (CAS 1015591-57-7)
Recommended Standards
- 4-Chloro-5-Isothiazolecarboxylic Acid (CAS 88982-87-0)
- 5-Chloro-1,2,3-thiadiazole-4-carboxamide (CAS 64837-51-0)
- 4-Chloro-2-oxo-2,3-dihydro-1,3-thiazole-5-carbaldehyde (CAS 55359-96-1)
- 5-Chloro-1,3,4-thiadiazole-2-carboxamide (CAS 64837-52-1)
- 4-Chloro-5-methyl-1H-indazole (CAS 152626-83-0)
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