Atazanavir Impurity 12 CAS 162536-40-5
| CAS No. | 162536-40-5 |
| Molecular Formula | C15H22ClNO3 |
| Molecular Weight | 299.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Atazanavir Impurity 12 (C15H22ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Atazanavir Impurity 12 (CAS 162536-40-5), a pharmacopoeial impurity reference standard (molecular formula C15H22ClNO3, MW 299.79 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atazanavir Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H22ClNO3 |
| Molecular Weight | 299.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Atazanavir Standards
- Atazanavir Impurity 14 (CAS 102123-74-0)
- Atazanavir Impurity 12 (CAS 198904-84-6)
- Atazanavir Impurity 23 (CAS 149451-80-9)
- Atazanavir Impurity N1 (Relative stereochemistry) (CAS 98818-34-9)
- Atazanavir Impurity 10 (CAS 98737-29-2)
- Atazanavir Impurity 11 (CAS 156474-22-5)
- Atazanavir Impurity 13 (CAS 98760-08-8)
- Atazanavir impurity 19 (CAS 156474-21-4)
Recommended Standards
- Sertraline Impurity 68 (CAS CATO-C4X-134468)
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- 3,4,5-Trichloro-2-(trichloromethyl)pyridine (CAS 1201-30-5)
- Fexofenadine Impurity 13 (CAS 1010812-98-2)
- Atogepant Impurity 93 (CAS CATO-C4X-328593)
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- Methyl 2-(4-(methylsulfonamido)phenoxy)benzoate (CAS 866020-12-4)
- Ibuprofen Impurity 35 (CAS 103775-30-6)
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- 1-Methanesulfonyl-2-methyl-benzene (CAS 23276-69-9)
- 3-Bromo-4-methyl-benzenethiol (CAS 19075-64-0)
- (R)-4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazoline (CAS 1256955-44-8)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com