4-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-3h-imidazo[4,5-c]pyridine CAS 1010902-27-8
| CAS No. | 1010902-27-8 |
| Molecular Formula | C12H11F2N3 |
| Molecular Weight | 235.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-3h-imidazo[4,5-c]pyridine (CAS 1010902-27-8) is a high-purity analytical reference standard with the molecular formula C12H11F2N3 and a molecular weight of 235.23 g/mol.
The molecular framework of 4-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-3h-imidazo[4,5-c]pyridine (C12H11F2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H11F2N3 |
| Molecular Weight | 235.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorophenyl Standards
- 4-(2,5-Difluorophenyl)-4,5,6,7-tetrahydro-3h-imidazo[4,5-c]pyridine (CAS 1010898-10-8)
- 4-(2,3-Difluorophenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 1010904-11-6)
- 2-(((3,5-Difluorophenyl)amino)methyl)phenol (CAS 1021049-70-6)
- 1-(2,4-Difluorophenyl)-4-oxocyclohexanecarbonitrile (CAS 1202006-91-4)
- 1-(3,5-Difluorophenyl)-4-oxocyclohexanecarbonitrile (CAS 1202006-94-7)
- 1-(3,4-Difluorophenyl)-4-oxocyclohexanecarbonitrile (CAS 1202006-95-8)
- 1-(2,4-Difluorophenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 125126-73-0)
- 2-(5-(2,4-Difluorophenyl)furan-2-yl)cyclopropan-1-amine (CAS 1315347-98-8)
Recommended Standards
- N-[(6-Fluoropyridin-2-yl)amino]-2-(1H-1,2,4-triazol-1-yl)ethanimidamide (CAS 477852-46-3)
- 2-(4-(Trifluoromethoxy)phenyl)ethanethioamide (CAS 1016725-27-1)
- n-(5-Amino-2-fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)acetamide (CAS 953897-50-2)
- 2-Amino-1,3-bis(carboxylethoxy)propane (CAS 1020112-73-5)
- 2-Benzoyl-5-chlorobenzaldehyde (CAS 61077-14-3)
- 1310936-61-8 3-(1-Ethyl-4-methoxy-1H-indol-2-yl)-1H-pyrazol-5-amine MFCD14281877 (CAS 1310936-61-8)
- (2-(3-Chlorophenyl)oxazol-4-yl)methanol (CAS 885272-83-3)
- 5-(Difluoromethyl)-3-iodo-4-methylpyridin-2-amine (CAS 1805961-79-8)
- 1,1-Dicyclopropylethan-1-ol (CAS 18895-50-6)
- 1-(2-bromo-4-methylphenyl)cyclohexan-1-amine hydrochloride (CAS 1909308-98-0)
- 1-(5-(Diethylamino)-2-methyl-4-propyl-4,5-dihydrofuran-3-yl)ethanone (CAS 88557-06-6)
- 2-(2-Oxo-2,3-dihydro-1h-pyrido[2,3-b][1,4]thiazin-1-yl)acetic acid (CAS 100637-46-5)
- (2-(Tert-butyl)cyclopropyl)boronic acid (CAS 680600-46-8)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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