n-(5-Amino-2-fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)acetamide CAS 953897-50-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including n-(5-Amino-2-fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)acetamide.

n-(5-Amino-2-fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)acetamide (CAS 953897-50-2), molecular formula C10H10FN5O and molecular weight 235.22 g/mol, is a CATO reference standard with documented purity and traceability.

n-(5-Amino-2-fluorophenyl)-2-(1h-1,2,4-triazol-1-yl)acetamide (C10H10FN5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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