6-[4-(difluoromethoxy)phenyl]-1-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011396-52-3
| CAS No. | 1011396-52-3 |
| Molecular Formula | C15H11F2N3O3 |
| Molecular Weight | 319.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 319.26 g/mol gives 6-[4-(difluoromethoxy)phenyl]-1-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-[4-(difluoromethoxy)phenyl]-1-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011396-52-3), a certified reference material (molecular formula C15H11F2N3O3, MW 319.26 g/mol) for analytical method development and quality control.
The molecular framework of 6-[4-(difluoromethoxy)phenyl]-1-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (C15H11F2N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-[4-(difluoromethoxy)phenyl]-1-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11F2N3O3 |
| Molecular Weight | 319.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related difluoromethoxy Standards
- 4-(3-(Difluoromethoxy)phenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1354705-05-7)
- 4-(4-(Difluoromethoxy)phenoxy)-3-(trifluoromethyl)aniline (CAS 87294-32-4)
- 2-(2-(Difluoromethoxy)-7-methylquinoxalin-5-yl)-4-vinylthiazole (CAS 2172976-89-3)
- 2-(Difluoromethoxy)-4-iodonaphthalene (CAS 1261627-73-9)
- 1-(Difluoromethoxy)-3-iodonaphthalene (CAS 1261799-22-7)
- 1-(4-(Difluoromethoxy)phenyl)-5-phenyl-1,3-dihydro-2H-imidazole-2-thione (CAS 1105190-29-1)
- 6-[4-(difluoromethoxy)phenyl]-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1011398-65-4)
- 6-(3-(Difluoromethoxy)phenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1174858-05-9)
Recommended Standards
- Levofloxacin Impurity 94 (CAS CATO-C4X-137194)
- Methyl 5-((6,8-difluoro-4-oxoquinolin-1(4H)-yl)methyl)furan-2-carboxylate (CAS 1217116-85-2)
- Levofloxacin impurity 01 (CAS 154228-18-9)
- N-[4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]-N-methylpropan-2-amine (CAS 934586-45-5)
- 7'-(Trifluoromethyl)-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] (CAS 1314780-69-2)
- 1378039-78-1 4-azido-5-fluoropyridine-3-carbaldehyde KS-000024G6 (CAS 1378039-78-1)
- 3-((1-(3-Fluorophenyl)ethyl)amino)propan-1-ol (CAS 1042574-74-2)
- Levocetrizine Imine Impurity (CAS 2362-79-0)
- Methyl2,5-dibromofuran-3-carboxylate (CAS 1150271-26-3)
- 3-(4-Chloro-3-nitrophenyl)-5-(pyridin-4-yl)-1,2,4-oxadiazole (CAS 879452-13-8)
- 3,4-Difluoro-5-methylbenzoyl chloride (CAS 1806332-90-0)
- 8-Phenyl-4,9-dihydropyrazolo[1,5-d][1,2,4]triazinone (CAS 135131-00-9)
- 2-(3-Methoxyphenyl)spiro[3.3]heptan-2-amine (CAS 1491913-72-4)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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