1-(Difluoromethoxy)-3-iodonaphthalene CAS 1261799-22-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1261799-22-7
Molecular FormulaC11H7F2IO
Molecular Weight320.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(Difluoromethoxy)-3-iodonaphthalene CAS 1261799-22-7 chemical structure

Description

The occurrence of 1-(Difluoromethoxy)-3-iodonaphthalene is closely related to a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(Difluoromethoxy)-3-iodonaphthalene (CAS 1261799-22-7), molecular formula C11H7F2IO and molecular weight 320.07 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(Difluoromethoxy)-3-iodonaphthalene (C11H7F2IO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(Difluoromethoxy)-3-iodonaphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H7F2IO
Molecular Weight320.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF/I-containing

Related Difluoromethoxy Standards

Recommended Standards

Why CATO?