6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid CAS 1011399-33-9
| CAS No. | 1011399-33-9 |
| Molecular Formula | C21H14F3N3O3 |
| Molecular Weight | 413.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-33-9), molecular formula C21H14F3N3O3 and molecular weight 413.35 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C21H14F3N3O3, 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 413.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H14F3N3O3 |
| Molecular Weight | 413.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related difluoromethoxy Standards
- 1-[2-(Difluoromethoxy)benzyl]-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole (CAS 1515924-46-5)
- N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide (CAS 245747-71-1)
- 1-((2-(4-(Difluoromethoxy)Phenyl)-2-Methylpropoxy)Methyl)-3-(4-Fluorophenoxy)Benzene (CAS 80843-63-6)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-93-1)
- N-(4-(Difluoromethoxy)-3-methoxybenzyl)-2-(1,3-dioxoisoindolin-2-yl)-N-methylpropanamide (CAS 865278-12-2)
- 3-(4-(Difluoromethoxy)phenyl)-1-(furan-2-yl)-3-(quinolin-8-ylthio)propan-1-one (CAS 325474-43-9)
- Methyl 6-(4-(difluoromethoxy)phenyl)-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011400-18-2)
- 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-92-4)
Recommended Standards
- N-(3,5-Dichlorophenyl)-2-((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 561294-87-9)
- Copper iodate (CAS 13454-89-2)
- N-(2,5-Dichlorophenyl)-2-((4-ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 565464-68-8)
- 6-bromo-8-fluoroquinazolin-4-yl 4-methylbenzene-1-sulfonate (CAS 1384430-21-0)
- 6-Hydroxymelatonin β-D-glucuronide, 97% (CAS 94840-69-4)
- N-(1-Cyanocyclohexyl)-2-((4-phenylthiazol-2-yl)thio)acetamide (CAS 851284-71-4)
- Methyl 6-bromo-1H-indazole-7-carboxylate (CAS 2306272-13-7)
- 2,4-Dibromo-5-fluorophenylacetic acid (CAS 1806345-98-1)
- (2-AMINO-6-BROMOPYRIDIN-3-YL)METHANOL (CAS 1620239-70-4)
- 3-Chloro-4-methyl-N-(thiazol-5-ylmethyl)aniline (CAS 1343928-83-5)
- 2-({2-[(1-hydroxybutan-2-yl)amino]ethyl}amino)butan-1-ol (CAS 3577-94-4)
- Etrasimod Impurity 77 (CAS CATO-C4X-321477)
- 2-(Difluoromethyl)-3-iodopyridine-4-acetic acid (CAS 1805280-44-7)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
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