1-[2-(Difluoromethoxy)benzyl]-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole CAS 1515924-46-5
| CAS No. | 1515924-46-5 |
| Molecular Formula | C22H25BF2N2O3 |
| Molecular Weight | 414.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 414.25 g/mol gives 1-[2-(Difluoromethoxy)benzyl]-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-[2-(Difluoromethoxy)benzyl]-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole (CAS 1515924-46-5), a certified reference material (molecular formula C22H25BF2N2O3, MW 414.25 g/mol) for analytical method development and quality control.
1-[2-(Difluoromethoxy)benzyl]-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole (C22H25BF2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25BF2N2O3 |
| Molecular Weight | 414.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethoxy Standards
- 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-33-9)
- N-(4-(5-(Difluoromethoxy)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-3-fluoroisonicotinamide (CAS 245747-71-1)
- 1-((2-(4-(Difluoromethoxy)Phenyl)-2-Methylpropoxy)Methyl)-3-(4-Fluorophenoxy)Benzene (CAS 80843-63-6)
- N-(4-(Difluoromethoxy)-3-methoxybenzyl)-2-(1,3-dioxoisoindolin-2-yl)-N-methylpropanamide (CAS 865278-12-2)
- Methyl 6-(4-(difluoromethoxy)phenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-93-1)
- 3-(4-(Difluoromethoxy)phenyl)-1-(furan-2-yl)-3-(quinolin-8-ylthio)propan-1-one (CAS 325474-43-9)
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- 6-[4-(difluoromethoxy)phenyl]-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-92-4)
Recommended Standards
- 2-(2-(4-Bromophenyl)-5,8-dioxaspiro-[3.4]octan-2-yl)isoindoline-1,3-dione (CAS 1199556-86-9)
- 2-(2-Bromo-4-formyl-6-methoxyphenoxy)-N-(naphthalen-1-yl)acetamide (CAS 692279-89-3)
- tert-Butyl 5-iodo-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate (CAS 2382973-41-1)
- 2-(5-Bromo-4-formyl-2-methoxyphenoxy)-N-(naphthalen-1-yl)acetamide (CAS 832674-61-0)
- Acetaminosalol (CAS 118-57-0)
- 3beta-Tetrahydrocortisol 3,21-Diacetate (CAS 6820-57-1)
- (R)-5-Benzyl-2-(perfluorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate (CAS 1072808-07-1)
- 2,4-Bis(4-methylpiperazin-1-yl)aniline (CAS 797813-15-1)
- 2-Methyl-2-(5-methylpyridin-2-yl)propan-1-amine (CAS 929022-01-5)
- 6-Chloro-N-(tetrahydro-2H-thiopyran-4-yl)pyridin-3-amine (CAS 1545320-55-5)
- Ethyl 2-({5-methoxy-4-[3-(trifluoromethyl)phenoxy]pyrimidin-2-yl}sulfanyl)acetate (CAS 338423-35-1)
- n-(3-Methylbutan-2-ylidene)hydroxylamine (CAS 600-20-4)
- 5,6-Dichloro-2-(2-chloropyridin-3-yl)-1-(4-methoxybenzyl)-1H-benzo[d]imidazole (CAS 338774-36-0)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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