3-(piperidin-4-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine CAS 1011407-34-3
| CAS No. | 1011407-34-3 |
| Molecular Formula | C12H20N4 |
| Molecular Weight | 220.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(piperidin-4-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine (CAS 1011407-34-3), molecular formula C12H20N4 and molecular weight 220.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(piperidin-4-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine (C12H20N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 3-(piperidin-4-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20N4 |
| Molecular Weight | 220.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 4 |
Related piperidin Standards
- [(1-Benzyl-piperidin-4-yl)-cyclopropyl-amino]-acetic acid (CAS 1038367-87-1)
- 2-(Piperidin-1-ylmethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine (CAS 1174069-06-7)
- 4-Methyl-5-(1-(piperidin-1-yl)ethyl)pyrimidin-2-amine (CAS 1315367-43-1)
- N-(4-(Piperidin-1-yl)but-2-yn-1-yl)but-2-enamide (CAS 1396890-97-3)
- 6-(Piperidin-4-yl)-2-propylpyrimidin-4-amine (CAS 1707566-92-4)
- 2-(2-(Piperidin-1-yl)ethoxy)aniline (CAS 857373-29-6)
- 3-[2-(piperidin-1-yl)ethoxy]aniline (CAS 373824-23-8)
- 3-piperidin-3-yl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine (CAS 923164-14-1)
Recommended Standards
- 4-(4-Ethylmorpholin-2-yl)-2-methylaniline (CAS 1010384-56-1)
- Alpha,alpha-dithiocyanato-p-xylene (CAS 1014-99-9)
- [2,2'-Bipyridine]-4,4'(1H,1'H)-dithione (CAS 101028-40-4)
- 3-((2,6-Dimethylmorpholino)methyl)aniline (CAS 1016493-94-9)
- 8-Ethoxy-2-methylquinolin-4-ol (CAS 15644-92-5)
- 2-Chloro-6-cyanonicotinic acid (CAS 1356850-56-0)
- 1-(3,4-Dichlorobenzoyl)piperidin-4-one (CAS 223632-67-5)
- 4-(Difluoromethyl)-6-(3,4-dimethylphenyl)-2-hydrazinylpyrimidine (CAS 861225-97-0)
- Benzo[c]phenanthren-6-amine (CAS 4176-52-7)
- (3-Methyl-1,2,4-oxadiazol-5-yl)methanamine (CAS 90928-92-0)
- (S)-3-Amino-3-(3-bromophenyl)propan-1-olhydrochloride (CAS 1213186-22-1)
- 2-(2,6-Dichlorophenylmethoxy)phenylboronic acid (CAS 1256355-85-7)
- 4-(1,3-Dithian-2-yl)phenyl 4-bromobenzene-1-sulfonate (CAS 301194-00-3)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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