Bromo(4-chloro-2-fluorobenzyl)triphenylphosphorane CAS 101160-85-4
| CAS No. | 101160-85-4 |
| Molecular Formula | C25H20BrClFP |
| Molecular Weight | 485.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Bromo(4-chloro-2-fluorobenzyl)triphenylphosphorane is closely related to organophosphorus functionality, fluorine/chlorine/bromine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Bromo(4-chloro-2-fluorobenzyl)triphenylphosphorane (CAS 101160-85-4), molecular formula C25H20BrClFP and molecular weight 485.76 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C25H20BrClFP, Bromo(4-chloro-2-fluorobenzyl)triphenylphosphorane contains organophosphorus functionality, fluorine/chlorine/bromine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 485.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H20BrClFP |
| Molecular Weight | 485.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
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Recommended Standards
- Selumetinib Impurity 10 (CAS CATO-C4X-305310)
- 4-amino-1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]tetrahydrofuran-2-yl]-5-(hydroxymethyl)pyrimidin-2-one (CAS 1257247-39-4)
- 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-iodo-2-methylphenyl)acetamide (CAS 332904-32-2)
- CAS 327178-99-4 (CAS 327178-99-4)
- 2-Chloro-4-(cyclopropylmethoxy)pyridine (CAS 1341052-60-5)
- 9-Amino-8-hydroxy-5-methylnonyl hydrogen sulfate (CAS 80867-10-3)
- 3-(1-hydroxyethyl)-5-[(4-methoxyphenyl)methyl]-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one (CAS 2228971-14-8)
- Mebroqualone (CAS 4260-20-2)
- 2-Bromo-N,N-diethyl-5-(trifluoromethyl)benzenemethanamine (CAS 1414870-66-8)
- 1,2,5-thiadiazepane 1,1-dioxide (CAS 410545-38-9)
- Nicotinamide EP Impurity D (CAS 1453-82-3)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(2-chlorophenyl)methanone (CAS 1823182-32-6)
- (R)-3-(3-Bromophenyl)-2-hydroxypropionic Acid (CAS 1932233-01-6)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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