Nicotinamide EP Impurity D CAS 1453-82-3
| CAS No. | 1453-82-3 |
| Molecular Formula | C6H6N2O |
| Molecular Weight | 122.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nicotinamide EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Nicotinamide EP Impurity D (CAS 1453-82-3), a pharmacopoeial impurity reference standard (molecular formula C6H6N2O, MW 122.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C6H6N2O, Nicotinamide EP Impurity D contains an amide group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 122.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H6N2O |
| Molecular Weight | 122.12 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Nicotinamide Standards
- Nicotinamide cobalt chloride (CAS 6856-47-9)
- Nicotinamide EP Impurity C (CAS 1452-77-3)
- Nicotinamide (CAS 98-92-0)
- Nicotinamide Impurity 15 (CAS CATO-C4X-200015)
- Nicotinamide-2,4,5,6-d4 (CAS 347841-88-7)
- Nicotinamide, 1,4,5,6-tetrahydro- (CAS 7032-11-3)
- Nicotinamide-amide-<SUP>15</SUP>N (CAS 113950-01-9)
- Nicotinamide Impurity 6 (CAS 6960-22-1)
Recommended Standards
- 4-Nitrosoaniline (CAS 659-49-4)
- Glycopyrronium Bromide EP Impurity D (CAS 65-85-0)
- Bisoprolol EP Impurity S (CAS 123-08-0)
- Roxatidine Impurity 43 (CAS 100-83-4)
- Gefitinib Impurity 47 (CAS 3863-11-4)
- Ertugliflozin Impurity 2 (CAS CATO-C4X-30112)
- Paliperidone Impurity 162 (CAS CATO-C4X-1724162)
- 5-methyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1369131-37-2)
- 3-Bromo-5-fluoroquinolin-6-ol (CAS 1799434-51-7)
- 3-Cyclopropoxy-2-ethyl-5-(trifluoromethyl)pyridine (CAS 1243289-74-8)
- Tert-butyl (5-(hydroxymethyl)pyrazin-2-yl)carbamate (CAS 874476-55-8)
- 1-(1-(Cyclopropylmethyl)-1H-pyrazol-4-yl)ethan-1-amine (CAS 1341385-21-4)
- 3-Fluoro-2-formyl-5-methylbenzoic acid (CAS 2384415-10-3)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com