5-Chloro-3-ethyl-1,2,4-thiadiazole CAS 101258-23-5

Description

Compared with other compounds in its class, the molecular weight of 148.61 g/mol gives 5-Chloro-3-ethyl-1,2,4-thiadiazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Chloro-3-ethyl-1,2,4-thiadiazole (CAS 101258-23-5) is a high-purity analytical reference standard with the molecular formula C4H5ClN2S and a molecular weight of 148.61 g/mol.

The molecular framework of 5-Chloro-3-ethyl-1,2,4-thiadiazole (C4H5ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Chloro-3-ethyl-1,2,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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