Paroxetine EP Impurity G HCl CAS 1012886-75-7
| CAS No. | 1012886-75-7 |
| Molecular Formula | C12H14FN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Paroxetine EP Impurity G HCl (CAS 1012886-75-7), a pharmacopoeial impurity reference standard (molecular formula C12H14FNHCl, MW 227.71 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Paroxetine EP Impurity G HCl (C12H14FNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 227.71 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Paroxetine EP Impurity G HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14FN HCl |
| Molecular Weight | 227.71 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
- Paroxetine Impurity 53 (CAS 109887-53-8)
Recommended Standards
- Benzylpenicillin Potassium EP Impurity I potassium salt (CAS 31447-86-6)
- Cefazolin Impurity 83 (CAS CATO-C4X-157783)
- Loxoprofen Impurity 48 (CAS 80530-54-7)
- 2-(Difluoromethyl)quinoline (CAS 1075184-01-8)
- 3-(2-(3-Formyl-1H-indol-1-yl)acetamido)benzoic acid (CAS 886499-42-9)
- ETHYL 2-(4-(ETHYLAMINO)PHENYL)ACETATE (CAS 39718-92-8)
- 2-Benzyloxy-1-methyl-4-nitro-benzene (CAS 219492-11-2)
- 2-bromo-5-methoxy-4-(trifluoromethyl)benzenesulfonyl chloride (CAS 694514-20-0)
- 2-Methyl-2-(2,2,2-trifluoroethoxy)propan-1-amine (CAS 1249573-00-9)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com