4-(2-Chloro-4-(trifluoromethyl)phenoxy)-2-fluoroaniline CAS 101463-63-2
| CAS No. | 101463-63-2 |
| Molecular Formula | C13H8ClF4NO |
| Molecular Weight | 305.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-(2-Chloro-4-(trifluoromethyl)phenoxy)-2-fluoroaniline (C13H8ClF4NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 305.66 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-(2-Chloro-4-(trifluoromethyl)phenoxy)-2-fluoroaniline (CAS 101463-63-2), a certified reference material (molecular formula C13H8ClF4NO, MW 305.66 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8ClF4NO |
| Molecular Weight | 305.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(3-Chloro-4-fluorophenoxy)-5-(trifluoromethyl)-phenylamine (CAS 946728-05-8)
- 4-(3-Chloro-4-fluorophenoxy)-2-(trifluoromethyl)-phenylamine (CAS 946741-29-3)
- 4-(3-Chloro-4-fluorophenoxy)-3-(trifluoromethyl)-phenylamine (CAS 946662-83-5)
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Recommended Standards
- N-{7-chloro-2H,5H-indeno[5,6-d][1,3]dioxol-5-yl}-2,2,2-trifluoroacetamide (CAS 866040-67-7)
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- 5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1h-pyrazole-4-carboxamide (CAS 623584-48-5)
- (2,4-Dimethoxypyrimidin-6-yl)zinc pivalate (0.86 mmol/g) (CAS 1643792-49-7)
- 1-(4,6-Dimethylpyrimidin-2-yl)-3-(4-hydroxyphenyl)guanidine (CAS 332074-04-1)
- Methyl 2-(2-amino-6-oxo-1,6-dihydropyrimidin-4-yl)acetate (CAS 86944-08-3)
- 1-Cyclopropanecarbonyl-9b-phenyl-1H,2H,3H,5H,9bH-imidazo[2,1-a]isoindol-5-one (CAS 338414-92-9)
- 2-(5-Amino-2-oxo-1,2-dihydropyridin-1-yl)acetamide (CAS 1016766-53-2)
- 4-(Methylthio)-6-(pyridin-2-yl)-1,3,5-triazin-2-amine (CAS 175204-53-2)
- 2-(2-Aminoethyl)pyrimidin-4-amine (CAS 933703-17-4)
- 2-(2,2-Difluorocyclopropoxy)ethanol (CAS 1955499-83-8)
- 1-[2-(5-Bromo-4-methyl-thiazol-2-yl)-pyrrolidin-1-yl]-ethanone (CAS 1361112-87-9)
- 260442-65-7 (4-(3-Chloro-5-(trifluoromethyl)(2-pyridyl))piperazinyl)(phenylamino)methane-1-thione MFCD00170158 (CAS 260442-65-7)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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