2-Bromo-5-chlorothiophene-3-carbaldehyde CAS 1014644-76-8
| CAS No. | 1014644-76-8 |
| Molecular Formula | C5H2BrClOS |
| Molecular Weight | 225.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-5-chlorothiophene-3-carbaldehyde (CAS 1014644-76-8), molecular formula C5H2BrClOS and molecular weight 225.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-5-chlorothiophene-3-carbaldehyde (C5H2BrClOS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H2BrClOS |
| Molecular Weight | 225.49 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-Bromo-2-chlorothiophene-3-carbaldehyde (CAS 120759-16-2)
- 5-Bromo-3-chlorothiophene-2-carbaldehyde (CAS 1503406-39-0)
- 3-Bromo-5-chlorothiophene-2-carbaldehyde (CAS 403640-46-0)
- 4-bromo-5-chlorothiophene-2-carbaldehyde (CAS 390360-90-4)
- 4-Bromo-2-thiophenecarbonyl chloride 4-bromothiophene-2-carbonyl chloride 58777-65-4 (CAS 58777-65-4)
- 2-Bromo-2-cyclopentylacetyl chloride (CAS 99644-87-8)
- 5-Bromo-3-chloro-4-fluoropyridin-2-amine (CAS 2304366-53-6)
- 5-Bromo-3-chloro-6-fluoropyridin-2-amine (CAS 2857813-67-1)
Recommended Standards
- 4-Chloro-2-(pyrrolidin-1-yl)phenylboronic acid (CAS 2096330-86-6)
- 3-Chloropyridine-4-boronic acid, neopentyl glycol ester (CAS 915070-52-9)
- 2-Chloro-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)pyridine (CAS 350489-38-2)
- 2-Bromothiophene-3-carbonyl chloride (CAS 197370-13-1)
- 3-(9-(tert-Butyl)-8-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)pyrazolo[1,5-d][1,2,4]triazin-2-yl)-5-methylisoxazole (CAS 342652-67-9)
- Methyl 2-{[4-(4-methylphenyl)-3-oxo-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-5-yl]sulfanyl}acetate (CAS 312625-68-6)
- 1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-3-(thiophen-2-ylmethyl)urea (CAS 1209611-14-2)
- Etoricoxib Impurity 28 (CAS 5470-70-2)
- 2-(azetidin-1-yl)-6-bromopyridine (CAS 1288991-76-3)
- Ethyl 3-(4-bromo-1h-pyrazol-1-yl)-2-methyl-2-(methylamino)propanoate (CAS 1249510-80-2)
- Perindopril Impurity N2 t-Butylamine (CAS 82978-68-5)
- n-[2-(3-fluorophenyl)ethyl]cyclopentanamine hydrochloride (CAS 1384428-73-2)
- 2,2-dimethyl-3-phenoxypropan-1-ol (CAS 1991-46-4)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
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