Etoricoxib Impurity 28 CAS 5470-70-2
| CAS No. | 5470-70-2 |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Etoricoxib Impurity 28 (CAS 5470-70-2, C8H9NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Etoricoxib Impurity 28 (C8H9NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Etoricoxib Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib impurity 64 (CAS 65719-09-7)
- Etoricoxib Impurity 39 (CAS 2457-47-8)
- Etoricoxib Impurity 37 (CAS 38746-92-8)
- Etoricoxib impurity 59 (CAS 21684-59-3)
- Etoricoxib Impurity 49 (CAS 73312-69-3)
- Etoricoxib Impurity 90 (CAS CATO-C4X-108090)
- Etoricoxib Impurity 36 (CAS 874-87-3)
- Etoricoxib Impurity 78 (CAS 99055-63-7)
Recommended Standards
- Diclofenac Sodium Impurity 32 (CAS 4746-61-6)
- Mirabegron Impurity 74 (CAS 24008-62-6)
- Milrinone Impurity 24 (CAS CATO-C4X-109124)
- Mirabegron Impurity 73 (CAS 100-12-9)
- Orlistat Impurity 48 (CAS CATO-C4X-149948)
- Ulipristal Impurity 6 (CAS 1655514-74-1)
- Salmeterol Impurity 11 (CAS 1330076-52-2)
- Avanafil Impurity 126 (CAS CATO-C4X-1118126)
- 4-Isocyanato-3,5-dimethyl-1-phenyl-1H-pyrazole (CAS 637335-93-4)
- 1-(2-(Isopropylimino)-4-methyl-2,3-dihydrothiazol-5-yl)ethan-1-one (CAS 938001-19-5)
- N-(4-Chlorophenyl)-4-ethyl-4,5-dihydro-1,3-thiazol-2-amine (CAS 379728-05-9)
- 4-Nitro-N'-(4-nitrobenzoyl)benzohydrazide (CAS 4402-22-6)
- 2-Methyl-3-nitropyridine-6-acetamide (CAS 1806489-88-2)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com