7-Bromo-3-hydroxy-N-(3-morpholinopropyl)-2-naphthamide CAS 10155-48-3
| CAS No. | 10155-48-3 |
| Molecular Formula | C18H21BrN2O3 |
| Molecular Weight | 393.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Bromo-3-hydroxy-N-(3-morpholinopropyl)-2-naphthamide.
CATO supplies 7-Bromo-3-hydroxy-N-(3-morpholinopropyl)-2-naphthamide (CAS 10155-48-3), a certified reference material (molecular formula C18H21BrN2O3, MW 393.27 g/mol) for analytical method development and quality control.
The molecular framework of 7-Bromo-3-hydroxy-N-(3-morpholinopropyl)-2-naphthamide (C18H21BrN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Bromo-3-hydroxy-N-(3-morpholinopropyl)-2-naphthamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21BrN2O3 |
| Molecular Weight | 393.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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