N-(4-Bromo-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-sulfonamide CAS 166963-34-4
| CAS No. | 166963-34-4 |
| Molecular Formula | C16H13BrN2O3S |
| Molecular Weight | 393.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(4-Bromo-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-sulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(4-Bromo-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-sulfonamide (CAS 166963-34-4), molecular formula C16H13BrN2O3S and molecular weight 393.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-Bromo-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-sulfonamide (C16H13BrN2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Bromo-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13BrN2O3S |
| Molecular Weight | 393.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- (3-Amino-1-(methylsulfonyl)-1H-indol-2-yl)(4-bromophenyl)methanone (CAS 269075-59-4)
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- 2-Amino-4-(2,4-dichloro-6-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 334498-00-9)
- 6-(3-((4-Bromophenyl)sulfonyl)ureido)hexanoic acid (CAS 2044702-76-1)
- Quinolin-4-ylmethanethiol (CAS 77436-80-7)
- 8-Bromo-1-cyano-7-methylnaphthalene, 97% (CAS 250716-75-7)
- N-benzyl-2-chloro-N-(2-hydroxyethyl)acetamide (CAS 100129-49-5)
- 5-Methoxy-2-((tosyloxy)methyl)tetrahydrofuran-3-yl 4-methylbenzenesulfonate (CAS 60110-72-7)
- Amorolfine Impurity 84 (CAS CATO-C4X-154284)
- 1-(4-Ethoxyphenyl)-1H-tetrazole-5-thiol (CAS 15182-68-0)
- 4-Amino-2-mercaptobenzoic acid (CAS 78334-06-2)
- 1-Phenethyl-3-(pyridin-3-yl)thiourea (CAS 60572-54-5)
- 1-[(3,4-dimethoxyphenyl)methyl]-1h-pyrazol-5-amine (CAS 956353-25-6)
- α Bag Cell Peptide (1-9) (CAS 87549-52-8)
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