Etoposide Impurity 23 CAS 101648-63-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.101648-63-9
Molecular FormulaC20H20Cl4O10
Molecular Weight562.18 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Etoposide Impurity 23 CAS 101648-63-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 562.18 g/mol gives Etoposide Impurity 23 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Etoposide Impurity 23 (CAS 101648-63-9), a pharmacopoeial impurity reference standard (molecular formula C20H20Cl4O10, MW 562.18 g/mol) used for the identification and quantification of trace impurities in APIs.

Etoposide Impurity 23 (C20H20Cl4O10) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Etoposide Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H20Cl4O10
Molecular Weight562.18 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentCl-containing

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