Ethyl 6-bromo-4-chloro-8-fluoroquinoline-3-carboxylate CAS 1016691-47-6

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies Ethyl 6-bromo-4-chloro-8-fluoroquinoline-3-carboxylate (CAS 1016691-47-6), a certified reference material (molecular formula C12H8BrClFNO2, MW 332.55 g/mol) for analytical method development and quality control.

Ethyl 6-bromo-4-chloro-8-fluoroquinoline-3-carboxylate (C12H8BrClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), Ethyl 6-bromo-4-chloro-8-fluoroquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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