4-((6-Chloropyridin-3-yl)methyl)piperazin-2-one CAS 1016705-94-4
| CAS No. | 1016705-94-4 |
| Molecular Formula | C10H12ClN3O |
| Molecular Weight | 225.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-((6-Chloropyridin-3-yl)methyl)piperazin-2-one (C10H12ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4-((6-Chloropyridin-3-yl)methyl)piperazin-2-one (CAS 1016705-94-4), a certified reference material (molecular formula C10H12ClN3O, MW 225.67 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-((6-Chloropyridin-3-yl)methyl)piperazin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12ClN3O |
| Molecular Weight | 225.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyridin Standards
- (6-Chloropyridin-3-yl)(piperazin-1-yl)methanone (CAS 1240566-37-3)
- 4-[(2-chloropyridin-4-yl)methyl]piperazin-2-one (CAS 1248482-82-7)
- 1-(6-Chloropyridin-3-yl)-N'-hydroxycyclobutanecarboximidamide (CAS 1369513-85-8)
- 1-(6-Chloropyridin-3-yl)-cyclopentanecarboxylic acid (CAS 1505992-00-6)
- 1-[(6-chloropyridin-2-yl)amino]pyrrolidine-2,5-dione (CAS 1383626-20-7)
- 5-(2-chloropyridin-3-yl)-5-methylimidazolidine-2,4-dione (CAS 1421601-54-8)
- 1-((6-Chloropyridin-3-yl)methyl)-1,4-diazepane (CAS 1094726-14-3)
- 1-(6-Chloropyridin-3-yl)-3,5-dimethylpiperazine (CAS 1169699-29-9)
Recommended Standards
- 1H-Pyrazolo[3,4-d]pyrimidine-3-carbonitrile, 4-chloro-6-(methylthio)- (CAS 1379363-08-2)
- 5-(Chloromethyl)-1-propylpyrazolo[1,5-a]pyrimidin-7(1h)-one (CAS 1018165-86-0)
- Norfloxacin Impurity 44 (CAS 140700-98-7)
- (3-Chloro-4-hydroxyphenyl)(pyrrolidin-1-yl)methanone (CAS 1019361-97-7)
- 2-mercapto-3-(3-methoxypropyl)-4-oxo-3,4-dihydroquinazoline-7-carboxylic acid (CAS 871478-73-8)
- (Cyclobutanecarbonyl)valine (CAS 1102900-71-9)
- Ethyl 5-chloro-3-methylbenzofuran-2-carboxylate (CAS 119138-73-7)
- 4-(2,5-dimethyl-1H-pyrrol-1-yl)-1H-pyrazole (CAS 1156354-43-6)
- 3-Amino-4-(2,5-difluorophenyl)butanoic acid (CAS 1368122-55-7)
- 3-(1,1-difluoroethyl)bicyclo[1.1.1]pentan-1-amine;hydrochloride (CAS 1886967-27-6)
- 2-bromo-3-methyl-5-(trifluoromethyl)pyridine (CAS 1211520-05-6)
- 2-[2-(4-Hydroxypiperidin-1-yl)-ethyl]isoindole-1,3-dione (CAS 101620-61-5)
- (3AS,8aR)-2-(6-methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole (CAS 1532531-18-2)
- C-Peptide (Proinsulin) (CAS 59112-80-0)
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