2-(2-Bromo-4-fluorophenoxy)nicotinamide CAS 1016870-83-9
| CAS No. | 1016870-83-9 |
| Molecular Formula | C12H8BrFN2O2 |
| Molecular Weight | 311.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H8BrFN2O2, 2-(2-Bromo-4-fluorophenoxy)nicotinamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 311.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-(2-Bromo-4-fluorophenoxy)nicotinamide (CAS 1016870-83-9), a certified reference material (molecular formula C12H8BrFN2O2, MW 311.11 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8BrFN2O2 |
| Molecular Weight | 311.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
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Recommended Standards
- Crisaborole Impurity 31 (CAS CATO-C4X-202131)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethyl)-1H-indole (CAS 1072813-19-4)
- Crisaborole impurity 120 (CAS CATO-C4X-2021120)
- Ethyl 4-(bromomethyl)-3-(trifluoromethyl)benzoate (CAS 859027-01-3)
- Ethyl 2-(1,5-dimethyl-1H-pyrazole-3-carboxamido)thiazole-4-carboxylate (CAS 1013782-83-6)
- Methyl[(5-phenyl-1,2-oxazol-3-yl)methyl]amine hydrochloride (CAS 852227-91-9)
- 2,6-Dimethylheptan-4-amine hydrochloride (CAS 130996-65-5)
- (S)-1-Cyclopropylpropan-2-amine (CAS 1335734-62-7)
- 2-(Dibutylamino)-N-(5-methyl-2,3-dihydrobenzofuran-3-yl)acetamide (CAS 105801-56-7)
- N-(2,4-dichlorophenyl)-2-(2-methyladamantan-2-yl)acetamide (CAS 400083-17-2)
- 3,4-Dihydro-4-oxo-pyrido[3,4-d]pyrimidine-2-carboxylic Acid (CAS 869296-21-9)
- 2-Cyclopropyl-5,6,7,8-tetrahydroquinazolin-4-ol (CAS 1019017-03-8)
- 2-chloro-1-(4-ethoxyphenyl)propan-1-one (CAS 790270-99-4)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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