4-Bromo-2-(4-fluorophenoxy)benzoic acid CAS 1099687-77-0
| CAS No. | 1099687-77-0 |
| Molecular Formula | C13H8BrFO3 |
| Molecular Weight | 311.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Bromo-2-(4-fluorophenoxy)benzoic acid (CAS 1099687-77-0), molecular formula C13H8BrFO3 and molecular weight 311.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-2-(4-fluorophenoxy)benzoic acid (C13H8BrFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Bromo-2-(4-fluorophenoxy)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8BrFO3 |
| Molecular Weight | 311.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
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- 4-(3-Bromo-5-(trifluoromethyl)pyridin-2-yl)morpholine (CAS 1437433-05-0)
- ETHYL 2-BROMO-2-(2-(TRIFLUOROMETHYL)PHENYL)ACETATE (CAS 144632-94-0)
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Recommended Standards
- 4-(4-Bromophenoxy)-3-fluorobenzoic acid (CAS 1020999-94-3)
- 2-((3-Bromophenyl)amino)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1197481-18-7)
- 4-(N-Propylsulfamoyl)-2-trifluoromethylphenylboronic acid (CAS 2096329-81-4)
- 2-((2-Bromophenyl)amino)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1209239-06-4)
- (2-Fluoro-6-(2-methoxyethoxy)pyridin-3-yl)boronic acid (CAS 1253575-61-9)
- 3-(5-Chlorothiophen-2-yl)-4,5-dihydroisoxazole-5-carboxylic acid (CAS 1094380-46-7)
- 2-Acetyl-1,4-dihydroxyanthracene-9,10-dione (CAS 111649-79-7)
- n-(2-Hydroxy-2,3-dihydro-1h-inden-1-yl)acetamide (CAS 115146-09-3)
- 3,6-Dichloropyridazin-4-ol hydrochloride (CAS 1955519-50-2)
- 6-bromo-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 92276-38-5)
- 3-Bromo-5-(trifluoromethyl)pyridazine (CAS 1934462-24-4)
- Methyl 2-(1-(4-methoxybenzyl)piperidin-4-yl)acetate (CAS 946699-21-4)
- 1-(3-(Piperidin-1-yl)phenyl)ethanone (CAS 39911-01-8)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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