6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one CAS 1017144-66-9
| CAS No. | 1017144-66-9 |
| Molecular Formula | C16H15FN2O2 |
| Molecular Weight | 286.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one.
CATO supplies 6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 1017144-66-9), a certified reference material (molecular formula C16H15FN2O2, MW 286.30 g/mol) for analytical method development and quality control.
6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one (C16H15FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Amino-4-(4-fluorobenzyl)-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H15FN2O2 |
| Molecular Weight | 286.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 8-Amino-4-(4-fluorobenzyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one (CAS 1018277-89-8)
- Ethyl 3-amino-6-(difluoromethyl)-4-methylthieno[2,3-b]pyridine-2-carboxylate (CAS 438223-65-5)
- 3-[5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl]piperidine-2,6-dione (CAS 1015474-32-4)
- Ethyl 5-amino-4-cyano-1-(4-methoxyphenyl)-1H-pyrazole-3-carboxylate (CAS 1150164-12-7)
- Ethyl 5-amino-4-cyano-1-(3-methoxyphenyl)pyrazole-3-carboxylate (CAS 1150164-14-9)
- (S)-2-Amino-N-cyclopropyl-N-(3-(trifluoromethyl)benzyl)propanamide (CAS 1354002-08-6)
- (2Z)-2-Amino-3-[(E)-[(3,4,5-trimethoxyphenyl)methylidene]amino]but-2-enedinitrile (CAS 69519-12-6)
- 3-{[4-Amino-6-(dimethylamino)-1,3,5-triazin-2-yl]methyl}-1,3-benzoxazol-2(3H)-one (CAS 903589-48-0)
Recommended Standards
- (2E)-1-(2,5-Dimethoxyphenyl)-3-(2-fluorophenyl)prop-2-en-1-one (CAS 1004035-72-6)
- 1-[4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-amine (CAS 1018143-59-3)
- Siponimod Impurity 2 (CAS 957202-29-8)
- Sorafenib Impurity 11 (CAS 1129683-88-0)
- 80471-63-2 6375T36951 Epostane Epostane [USAN:INN:BAN] Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4alpha,5alpha,17beta)- 4,5-epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile (4alpha,5alpha,17beta) Win 32729 Epostano [Spanish] Epostanum [Latin] Epostano Epostanum UNII-6375T36951 Win 32,729 (CAS 80471-63-2)
- N-(2-{[(4-chlorophenyl)methyl]sulfanyl}-2-methylpropyl)benzamide (CAS 303144-65-2)
- 5-Bromo-6-methyl-2-(pyridin-2-yl)pyrimidin-4-ol (CAS 1240622-70-1)
- 2-[(4-ethoxyphenyl)formamido]acetic acid (CAS 51220-52-1)
- 3-Amino-4-methoxy-N-(pyridin-3-yl)benzene-1-sulfonamide (CAS 1041546-42-2)
- N-(2-cyclopropylpropyl)thietan-3-amine (CAS 1851645-69-6)
- 4-Chloro-2-(((2,5-difluorophenyl)amino)methyl)phenol (CAS 329777-78-8)
- 3-((4-Fluoro-3-(trifluoromethyl)benzyl)thio)-4-(4-fluorobenzyl)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 294853-45-5)
- (3-Chloro-2-fluoro-4-methylphenyl)boronic acid (CAS 2377608-77-8)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com