(3-Chloro-2-fluoro-4-methylphenyl)boronic acid CAS 2377608-77-8
| CAS No. | 2377608-77-8 |
| Molecular Formula | C7H7BClFO2 |
| Molecular Weight | 188.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Chloro-2-fluoro-4-methylphenyl)boronic acid (CAS 2377608-77-8) is a high-purity analytical reference standard with the molecular formula C7H7BClFO2 and a molecular weight of 188.39 g/mol.
Structurally, (3-Chloro-2-fluoro-4-methylphenyl)boronic acid (C7H7BClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 188.39 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7BClFO2 |
| Molecular Weight | 188.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (5-Chloro-2-fluoro-4-methylphenyl)boronic acid (CAS 1072952-42-1)
- 2-Chloro-4-fluoro-5-methylphenylboronic acid (CAS 1207428-93-0)
- (2-Chloro-6-fluorobenzyl)boronic acid (CAS 1350512-24-1)
- 2-Chloro-5-fluoro-4-methylphenylboronic acid (CAS 1612184-35-6)
- (3-Chloro-2-fluoro-5-methylphenyl)boronic acid (CAS 352535-88-7)
- (4-Chloro-2-fluoro-3-methylphenyl)boronic acid (CAS 944128-92-1)
- (4-Chloro-2-fluoro-5-methylphenyl)boronic acid (CAS 325786-09-2)
- (5-Chloro-2-fluoro-3-methylphenyl)boronic acid (CAS 352535-87-6)
Recommended Standards
- 1,2,3,5,6-Pentathiepane (CAS 292-46-6)
- [(2-Chloro-5-fluorophenyl)methyl]boronic acid (CAS 2246614-18-4)
- Butoxy(tertbutyl)dimethyl silane (CAS 37170-50-6)
- [(4-Chloro-2-fluorophenyl)methyl]boronic acid (CAS 2246683-95-2)
- 5-Chloro-2-hydroxy-4-methylbenzoic acid (CAS 35458-35-6)
- 2-Bromo-1-(difluoromethyl)-4-nitrobenzene (CAS 1261496-29-0)
- (4-Ethyl-1-methyl-1H-pyrazol-3-yl)methanol (CAS 1256561-12-2)
- N-(3-cyanofuro[3,2-b]pyridin-2-yl)thiophene-2-carboxamide (CAS 866039-04-5)
- 1H-Indole-3-carboximidamide hydrochloride (CAS 80661-60-5)
- (1R,2R)-2-methylcyclohexan-1-amine hydrochloride (CAS 302596-19-6)
- (1<I>R</I>,2<I>R</I>)-(+)-<I>N</I>,<I>N</I>′-dimethyl-1 ,2-bis[3-(trifluoromethyl)phenyl]ethylenediamine (CAS 137944-39-9)
- 5-Bromo-2-propoxypyridine (CAS 850142-79-9)
- N-(1-(Furan-2-yl)but-3-en-1-yl)-3,4-dimethoxyaniline (CAS 510721-36-5)
- Peptide 431 (CAS CATO-CPTD788431)
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