8-Iodoquinoline-2-carboxylic acid CAS 1017436-31-5
| CAS No. | 1017436-31-5 |
| Molecular Formula | C10H6INO2 |
| Molecular Weight | 299.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Iodoquinoline-2-carboxylic acid (C10H6INO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
8-Iodoquinoline-2-carboxylic acid (CAS 1017436-31-5), molecular formula C10H6INO2 and molecular weight 299.06 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Iodoquinoline-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6INO2 |
| Molecular Weight | 299.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodoquinoline Standards
- 6-Iodoquinoline-2-carboxylic acid (CAS 1017464-01-5)
- 7-Iodoquinoline-3-carboxylic acid (CAS 1416438-89-5)
- 6-Iodoquinoline-3-carboxylic acid (CAS 1416440-04-4)
- 8-Iodoquinoline-5-carboxylic acid (CAS 1427082-96-9)
- 3-Iodoquinoline-8-carboxylic acid (CAS 1934445-70-1)
- 7-Iodoquinoline-4-carboxylic acid (CAS 2138307-26-1)
- 8-Iodoquinoline-2,4(1H,3H)-dione (CAS 1025796-05-7)
- 6-Iodoquinoline-2,4(1H,3H)-dione (CAS 658709-62-7)
Recommended Standards
- 1,4-BIS(TRIFLUOROMETHYL)-2-BROMOBENZENE 1-BROMO-2,5-BIS(TRIFLUOROMETHYL)BENZENE 2,5-BIS(TRIFLUOROMETHYL)BROMOBENZENE 2-BROMO-1,4-BIS(TRIFLUOROMETHYL)BENZENE 7617-93-8 BC002741 (CAS 7617-93-8)
- 1Y702GD0FG 6419-19-8 Aminotrimethylene phosphonic acid (Nitrilotris(methylene))triphosphonic acid Nitrilotris(methylene)trisphosphonic acid Phosphonic acid, (nitrilotris(methylene))tris- Nitrilotrimethylenetris(phosphonic acid) Phosphonic acid, (nitrilotris(methylene))tri- Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris- 4-01-00-03070 (Beilstein Handbook Reference) AI3-51572 Amino, tris(methylene phosphonic acid) Aminotri(methylene phosphonic acid) Aminotri(methylenephosphonic acid) Aminotri(methylphosphonic acid) Aminotris(methanephosphonic acid) Aminotris(methylphosphonic acid) BRN 1715724 Dequest 2000 Dowell L 37 EINECS 229-146-5 Ferrofos 509 Nitrilotrimethanephosphonic acid Nitrilotrimethylenephosphonic acid Nitrilotrimethylphosphonic acid (Nitrilotris(methylene))trisphosphonic acid Nitrilotris(methylphosphonic acid) Tris(phosphonomethyl)amine UNII-1Y702GD0FG EC 229-146-5 Nitrilotris(methylenephosphonic acid) Phosphoric acid, (nitrilotris-(methylene))tris- (CAS 6419-19-8)
- 102153-71-9 2-Iodo-3-nitronaphthalene 7603AC C10H6INO2 (CAS 102153-71-9)
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- Ribociclib Impurity 25 (CAS CATO-C4X-310025)
- 4-Bromo-2-ethyl-5-methoxypyridine (CAS 877129-60-7)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
Why CATO?
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