Ribociclib Impurity 25 CAS CATO-C4X-310025
| CAS No. | CATO-C4X-310025 |
| Molecular Formula | C23H26N8O3 |
| Molecular Weight | 462.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ribociclib Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Ribociclib Impurity 25 (CAS CATO-C4X-310025), a pharmacopoeial impurity reference standard (molecular formula C23H26N8O3, MW 462.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Ribociclib Impurity 25 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 462.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H26N8O3 |
| Molecular Weight | 462.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Ribociclib Standards
- Ribociclib Impurity 9 (CAS 2460732-08-3)
- Ribociclib Impurity 10 (CAS CATO-C4X-310010)
- Ribociclib impurity 2 (CAS CATO-C4X-31002)
- Ribociclib Impurity 23 (CAS CATO-C4X-310023)
- Ribociclib Impurity 19 (CAS CATO-C4X-310019)
- Ribociclib Impurity N1 (CAS 2069953-39-3)
- Ribociclib Impurity 17 (CAS 2514753-27-4)
- Ribociclib Impurity 24 (CAS CATO-C4X-310024)
Recommended Standards
- Rimegepant Impurity 57 (CAS CATO-C4X-248757)
- Sar-Pro-Arg-pNA (CAS 77695-30-8)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
- Carbamic acid, N-[(1S)-2-[[(1S)-3-fluoro-2-oxo-1-(phenylmethyl)propyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester (CAS 105608-85-3)
- Brivaracetam Impurity 49 (CAS CATO-C4X-200749)
- Tolvaptan Impurity 76 (CAS 2458812-63-8)
- Almotriptan Impurity 3 (CAS 334981-13-4)
- Methyl 3-amino-3-(3,4-dimethoxyphenyl)propanoate (CAS 54503-20-7)
- Methyl (2S)-2-(2-aminoacetamido)-4-methylpentanoate (CAS 54793-73-6)
- 2-(2-Bromophenyl)piperazine (CAS 910444-36-9)
- 4-(1H-pyrrol-1-yl)pyridin-2-amine (CAS 1314354-37-4)
- 3-[(3,4-dimethylphenyl)amino]propanenitrile (CAS 36034-61-4)
- N,4,6-trimethylpyridin-2-amine (CAS 99132-30-6)
- Calcium-Like Peptide 3 (CAS 261969-05-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com