2-Methoxy-5-(trifluoromethoxy)cinnamic acid CAS 1017779-14-4
| CAS No. | 1017779-14-4 |
| Molecular Formula | C11H9F3O4 |
| Molecular Weight | 262.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Methoxy-5-(trifluoromethoxy)cinnamic acid (CAS 1017779-14-4), a certified reference material (molecular formula C11H9F3O4, MW 262.18 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-Methoxy-5-(trifluoromethoxy)cinnamic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Methoxy-5-(trifluoromethoxy)cinnamic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9F3O4 |
| Molecular Weight | 262.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Methoxy Standards
- (E)-3-(4-methoxy-3-(trifluoromethoxy)phenyl)acrylic acid (CAS 1262018-46-1)
- 3-(2-Methoxy-4-(trifluoromethoxy)phenyl)acrylic acid (CAS 1262019-21-5)
- 2-Methoxy-5-(pentafluoro-λ6-sulfanyl)benzaldehyde (CAS 1240256-83-0)
- 6-Methoxy-5,6-dihydro-2H-pyran-3-yl trifluoromethanesulfonate (CAS 2843587-05-1)
- 2-(2-Methoxy-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1134082-52-2)
- 2-(4-Methoxy-2,6-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1208459-72-6)
- 2-(3-Methoxy-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1218790-19-2)
- 2-(4-Methoxy-2,3-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 915402-04-9)
Recommended Standards
- 5-Bromo-N-cyclohexyl-1,3,4-thiadiazol-2-amine (CAS 63555-69-1)
- Dimethyl 2-(trifluoromethyl)terephthalate (CAS 102867-06-1)
- 5-Bromo-2-(morpholin-4-ylmethyl)thiophene (CAS 364793-76-0)
- Methyl 3-Oxo-3-[3-(trifluoromethoxy)phenyl]propionate (CAS 1181574-09-3)
- 4-Bromo-6-fluoro-2-(hydroxymethyl)benzimidazole (CAS 1935913-37-3)
- 1-(3,4-Dicarboxyphenyl)-4-hydroxypyridinium chloride (CAS 1446198-07-7)
- 2-((1-Methyl-1h-tetrazol-5-yl)thio)-1-(thiophen-2-yl)ethan-1-one (CAS 380166-43-8)
- 2-Bromo-4H-cyclopenta[b]thiophen-6(5H)-one (CAS 13191-41-8)
- 2,3-Dichloro-6-fluoro-7-methylquinoxaline (CAS 1217303-99-5)
- ethyl 3-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1239964-19-2)
- 6-Propyl-5,6,7,8-tetrahydro-1,6-naphthyridin-3-ol (CAS 1708401-24-4)
- 2-Amino-2-(2,4-difluorophenyl)acetic Acid (CAS 240409-02-3)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with butyl 2-propenoate, ethenylbenzene, 2-hydroxyethyl 2-propenoate and 2-propenoic acid (CAS 26061-99-4)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com