4-Ethoxy-2,6-difluorophenol CAS 1017779-55-3
| CAS No. | 1017779-55-3 |
| Molecular Formula | C8H8F2O2 |
| Molecular Weight | 174.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Ethoxy-2,6-difluorophenol (CAS 1017779-55-3), a certified reference material (molecular formula C8H8F2O2, MW 174.14 g/mol) for analytical method development and quality control.
4-Ethoxy-2,6-difluorophenol (C8H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Ethoxy-2,6-difluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O2 |
| Molecular Weight | 174.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 3-Ethoxy-2,4-difluorophenol (CAS 1017778-14-1)
- 4-Ethoxy-3,5-difluorophenol (CAS 1017779-45-1)
- 2-Ethoxy-3,5-difluorophenol (CAS 1017779-78-0)
- 3-Ethoxy-2,6-difluorophenol (CAS 1092461-31-8)
- 4-Ethoxy-2,3-difluorophenol (CAS 126163-56-2)
- 5-Ethoxy-2,4-difluorophenol (CAS 1881295-97-1)
- 4-Ethoxy-2,5-difluorophenol (CAS 612092-32-7)
- 6-Ethoxy-5-fluorouracil (CAS 522654-10-0)
Recommended Standards
- 3,6-Difluoro-1,2-benzenedimethanol (CAS 1092449-21-2)
- Olaparib Impurity 103 (CAS 2691818-05-8)
- 862415-66-5 1-[(~13~C_3_)Propanoyloxy]pyrrolidine-2,5-dione DTXSID10745874 (CAS 862415-66-5)
- 4-(2,2-Difluoroethoxy)phenol (CAS 1183003-98-6)
- 2-((5-Bromopyridin-3-yl)oxy)-N,N-dimethylacetamide (CAS 1341807-16-6)
- (R)-1-(benzyloxy)butan-2-amine (CAS 142559-11-3)
- 1-Hydroxynaphthalene-2-sulfonyl chloride (CAS 102879-07-2)
- N-(sec-Butyl)-2-(2-methylphenoxy)-1-butanamine (CAS 1040692-42-9)
- Ethyl 6-chloro-8-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 1983011-76-2)
- Potassium 2-amino-2-oxoacetate (CAS 21141-31-1)
- 2-(7-(4-Chlorobenzoyl)-5-oxo-2,3,5,6-tetrahydropyrrolo[2,1-b]thiazol-6-yl)acetic acid (CAS 118792-68-0)
- 6-Ethynyl-8-phenylimidazo[1,2-a]pyrazine (CAS 2227272-60-6)
- Isochroman-7-amine (CAS 1391224-90-0)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
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