2-Ethoxy-3,5-difluorophenol CAS 1017779-78-0
| CAS No. | 1017779-78-0 |
| Molecular Formula | C8H8F2O2 |
| Molecular Weight | 174.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Ethoxy-3,5-difluorophenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Ethoxy-3,5-difluorophenol (CAS 1017779-78-0), molecular formula C8H8F2O2 and molecular weight 174.14 g/mol, is a CATO reference standard with documented purity and traceability.
2-Ethoxy-3,5-difluorophenol (C8H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Ethoxy-3,5-difluorophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8F2O2 |
| Molecular Weight | 174.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Ethoxy Standards
- 3-Ethoxy-2,4-difluorophenol (CAS 1017778-14-1)
- 4-Ethoxy-3,5-difluorophenol (CAS 1017779-45-1)
- 4-Ethoxy-2,6-difluorophenol (CAS 1017779-55-3)
- 3-Ethoxy-2,6-difluorophenol (CAS 1092461-31-8)
- 4-Ethoxy-2,3-difluorophenol (CAS 126163-56-2)
- 5-Ethoxy-2,4-difluorophenol (CAS 1881295-97-1)
- 4-Ethoxy-2,5-difluorophenol (CAS 612092-32-7)
- 6-Ethoxy-5-fluorouracil (CAS 522654-10-0)
Recommended Standards
- 3,6-Difluoro-1,2-benzenedimethanol (CAS 1092449-21-2)
- 4-(2,2-Difluoroethoxy)phenol (CAS 1183003-98-6)
- Olaparib Impurity 103 (CAS 2691818-05-8)
- 2-(Difluoromethyl)-4-methoxyphenol (CAS 1242172-87-7)
- 5-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid (CAS 1202993-11-0)
- 6-Chloro-1-methylindolin-2-one (CAS 156136-55-9)
- 2-bromo-4-cyclopropoxy-1-fluorobenzene (CAS 1243469-64-8)
- tert-Butyl hept-6-en-1-ylcarbamate (CAS 284670-71-9)
- Phloroglucinol Impurity 16 (CAS 902146-43-4)
- (1S,4s)-4-amino-N-methylcyclohexane-1-carboxamide hydrochloride (CAS 2270911-51-6)
- 1,4,7,10,13,16,19,22-Octaoxacyclotetracosane (CAS 33089-37-1)
- (3R,4S,5S,6R)-2-(decyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 141464-42-8)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com